Izindlela zokuvimbela inzalo amaphilisi "Belarus": ukubuyekezwa odokotela, buhle, nebubi, Izimo isincomo udokotela

Kungakhathaliseki imithi ethile kuyaphumelela "Belarus"? Uphenyo odokotela (elithola, nebubi) ethulwa ngezansi. Uyofunda mayelana kwindlela ekhiqizwa izidakamizwa, izithako liqukethe, uma unazo contraindications engemihle.

Incazelo, ukubunjwa, ukuma, emaphaketheni

Ukulungiswa "Belarus" itholakale ukudayiselwa ngesimo esiyindilinga biconvex ukukhanya pink amaphilisi nge core emhlophe. Kuhlanganisa ezifana izingxenye esebenzayo njengoba chlormadinone acetate futhi ethinyl estradiol. Futhi, iqukethe izithako engeziwe ngesimo monohydrate lactose, povidone, corn isitashi kanye magnesium stearate.

Ngokuphathelene pink ifilimu elingenamikhono, ukuthi liqukethe titanium dioxide, talc, hypromellose, monohydrate lactose, macrogol 6000, propylene glycol futhi colorant obomvu oxide ferric.

Ngo kokudayiswa lweminikelo e ibhamuza amaphakethe, okuyinto equkethwe ebhokisini elenziwe amakhadibhodi.

pharmacodynamics

Uyini izidakamizwa "Belarus"? Uphenyo odokotela (elithola, nebubi zomuthi izokwethulwa kamuva) bathi it is a elihlangene umuthi, senzelwe abaphathi ngomlomo.

ukusetshenziswa isikhathi eside amaphilisi kunciphisa uketshezi of luteinizing futhi i-hormone follicle-kuqabula futhi, ngenxa yalokho, kuvimbela ukukhiqizwa kwamaqanda. Futhi, lolu izidakamizwa ikhuthaza ekwandeni futhi secretory tingucuko endometrium. ukuchayeka okunjalo kuvimbela sokuhlanganiswa iqanda eselivundisiwe.

Lapho ethola nomuthi kubhekwe kwandisa viscosity uketshezi lwamafinyila kusukela wesibeletho lesizalo. Ngenxa wesilisa ocansini amaseli nge nobunzima idlule insikazi izitho zangasese.

Kungokwalabo asebenzayo izidakamizwa chlormadinone acetate kuyinto progestin esesikhundleni izakhiwo protivoandrogennymi. Uyakwazi ancintisane androgens at receptor ethize, futhi ngaleyo ndlela buthaka ukusebenza kwabo.

Ithuba sokukhulelwa ngonyaka uyahluka 0.29-0.69%, futhi ancike ekuhambisaneni eziyalezweni nokushintsha kokudla nokufakwa kanye nokuphathwa izidakamizwa.

Pharmacokinetics

"Belara" Tablets ukuqukatha izinto ezimbili. imingcele yabo kinetic zihluke kakhulu:

• Chlormadinone acetate angabacwasi ngokushesha futhi ngokuphelele ugxile kusukela pheshana emathunjini. okuhlushwa sakhe esikhulu kunazo zonke e-igazi ihora nesigamu. Cishe ama 95% we ketshezi nakanjani plasma amaprotheni (ikakhulukazi albumin).

Lapho ukuguqulwa ingxenye kwakhiwa metabolites eziningana (3-alpha- ne-beta-3-hydroxy-chlormadinone acetate).

Ingxenye-ukuphila kwalesi isici amahora 33. Chlormadinone acetate futhi metabolites zalo excreted imali belingana umchamo kanye endleni.

• Ethinyl estradiol nayo ngokushesha futhi ngokuphelele ugxile kusukela esiswini. esiphezulu plasma lokuhlushwa wayo kufinyelelwe emva kwemizuzu 90. bioavailability Ingabe Ohulumeni Banalo Lonke we ketshezi kuyinto 40%.

Cishe u-98% ethinyl estradiol lihlotshaniswa amaprotheni kwegazi. Yena uguqulwa esebenzisa hydroxylation esiyingini elimnandi. I esuselwe eziyisisekelo yalolu ketshezi wenza 2-hydroxy-ethinyl estradiol.

Ingxenye-ukuphila esemazweni kuyinto amahora 13. Lokukhipha ke nge indle nezinso e isilinganiso 3: 2.

Ukuze uvimbele ngokugcwele yi-ovulation, chlormadinone acetate kufanele kuqashelwe isamba 1.7 mg nsuku zonke. Isikali ngoba umjikelezo ephelele imayelana 25 mg.

izinkomba

Tablets "Belarus" zihloselwe kuphela ubulili bubuhle. Basuke adingekayo zokuvimbela inzalo ngomlomo.

Izimo

Kungaphansi kwaziphi izimo akufanele bathathe imithi "Belarus"? Uphenyo odokotela (elithola, bawo yaleli luhlobo kufanele inake wonke abesifazane) ukubika ukuthi izidakamizwa ingasetshenziswa hhayi uma:

• Thrombosis futhi thromboembolism (embolism yamaphaphu, isilethikusebenza, thrombosis emithambo yegazi, izinguquko cerebrovascular);
• kuhlelwe kokungenela kuhlinzwa (inyanga ngaphambi), kanye esikhathini immobilization;
• nomfutho wegazi ophezulu engalawuliwe;
• izimpawu eyinhloko thrombosis noma thrombophlebitis, kanye nezimpawu embolism (kuhlanganise ukuhlaselwa ischemic yesikhashana);
• umonakalo ezinzima isibindi oyingozi noma ezingamahlalakhona;
• sikashukela engalawuliwe;
• Ukulunywa wonke umzimba, cholestasis;
• nezici ezithile ukuze ukuvela lwemithambo futhi thrombosis emithambo yegazi;
• ezinzima epigastric ubuhlungu, hepatomegaly noma izimpawu ukopha naphakathi-besisu;
• izimila isibindi;
• ukuhlaselwa migraine;
• Rotor syndrome noma isifo Dubin-Johnson decelerating outflow ka Bile;
• motor iziyaluyalu;
• iziyaluyalu sezinzwa imvelo acute;
• porphyria;
• ama-hormone engaphansi umdlavuza noma okusolekayo;
• yokucindezeleka okukhulu;
• pancreatitis;
• amenorrhea cryptogenic;
• izinguquko liphinyiselwe umzimba lipid;
• lactation;
• okwandisa ukuvama zesifo sokuwa;
• ukhulelwe;
• Yiqiniso eyinkimbinkimbi yama otosclerosis, kuhlanganise phakathi ukukhulelwa kwangaphambili;
• umlutha ukubhema (e iziguli ezivela engu-35);
• Hyperplasia endometrial;
• zokungezwani ne-lactose, lactase ukuntula nezinhlayiyana zikashukela-galactose malabsorption;
• ukopha lwesitho sangasese sowesifazane umsuka engaziwa;
• khona sebuningini engcupheni emithambo yegazi noma lwemithambo thrombosis;
• sensitization ukuze ketshezi izidakamizwa.

Indlela aphuze iphilisi "Belarus"?

Ngokusho imiyalelo, nephilisi lokuvimbela inzalo , ezithathwe ngomlomo, ngaphandle ukuhlafuna futhi ngiphuza amanzi kancane. Indlela ukuqhuba yokwamukela? "Belarus" Kumele kuthathwe nsuku zonke ngesikhathi esifanayo (kusihlwa).

Isikhathi izidakamizwa ekuphathweni izinsuku ezingu-21. Ngaphezu kwalokho, kudingeka kuphazamiseke okwesikhathi ngesonto. Ngemva cishe 2-4 izinsuku emva iphilisi zokugcina siyenzeka ukopha esesikhathini.

Ngemva kwezinsuku eziyisikhombisa iyadingeka ukuqala ethola izidakamizwa nge batch ezahlukene, kungakhathaliseki ukopha ime noma cha.

Ithebhulethi yokuqala kufanele asetshenziswe usuku 1 st lomjikelezo bokuphila (ie ngosuku lokuqala ukuya esikhathini esilandelayo). Kuphela kuleli cala, inzalo iqala ukusebenza yayo ihlala ngisho ikhefu esingangesonto.

Nokho, ithebhulethi yokuqala zingafundwa ngosuku 2-5 of umjikelezo wokuya esikhathini. Kulokhu, phakathi nezinsuku zokuqala 7 ukusetshenziswa futhi isithiyo zindlela zokuvimbela inzalo zingqubuzana.

Uma isikhathi sakho waqala izinsuku ezingaphezu kwezingu-5 edlule, kubalulekile ukulinda olandelayo, bese kuphela uqhubekele umjikelezo yokwamukela amaphilisi.

side effects

Manje ngoba sewuyazi ukuthi kanjani ukuphuza iphilisi. Kufanele kukhunjulwe ukuthi kokuthatha lesi izidakamizwa kungabangela imiphumela elandelayo uhlangothi:

• uvalo, ukucasuka, isimo sokucindezeleka, libido kuyadamba;
• isifiso sokudla kakhulu, izinguquko Ukwakheka lipid wegazi;
• hypersensitivity kuya izidakamizwa;
• ukungabekezelelani ukuba contact lens, ukuphazamiseka visual, conjunctivitis, tinnitus, ukulahlekelwa kukuzwa;
• isiyezi, ubuhlungu migraine;
• umthambo thrombosis, umfutho wegazi ophakeme, nciphisa, hypotension, emithanjeni varicose, umfutho ophakeme wegazi,
• ukubuyisa, ubuhlungu besisu, isicanucanu, uhudo, ukuhlanza;
• ukuqubuka, induna, erythema, chloasma, ukuqubuka, nezinwele, lesikhumba iziyaluyalu, eczema;
• lumbodynia, umuzwa wobukhulu, imisipha iziyaluyalu;
• candidiasis lwesitho sangasese sowesifazane, dysmenorrhea, vulvovaginitis, kakhudlwana osenyameni lwesitho sangasese sowesifazane, premenstrual syndrome, amenorrhea, fibroadenoma kwebele, ubuhlungu esiswini.

izidakamizwa ekuhlanganyeleni

Kungenzeka yini ukuba sihlanganise umuthi "Belarus" nezinye izidakamizwa? Ukusetshenziswa kwalezi amaphilisi nabanye ingawenza buthaka ukusebenza kwabo. imithi enjalo obuqand zihlanganisa:

• izidakamizwa isebenze hepatic microsomal enzyme;
• ejenti ukuthi ukwandisa motility emathunjini;
• abanye antibiotic.

Emva "Belarus" futhi wamukele lezi zimali ukusebenzisa izindlela ezengeziwe inzalo.

Inani kanye analogue

Analogue kubhekwe ekwakhiweni yilezi ezilandelayo: "Widor", "Daila", "Jess", "Difenda", "Janine", "Lindinet 20", "LOGEST", "Mersilon", "Milanda", "Modell Tin", "Novinet "" Silest "," Femoden "," Yarina Plus ".

Njengoba amanani, incike inani amaphilisi iphakethe ngalinye. Izindleko Isilinganiso "Belarus" umuthi ruble 490-530 (21 nama-PC.).

"Belarus": ukubuyekezwa odokotela (elithola, nebubi)

Ngokwe-art, izidakamizwa "Belara" wazibonakalisa indlela enokwethenjelwa kakhulu inzalo. Lapho lwamukelwa kahle ukukhulelwa okungafunwa ayifakiwe. Nokho, lokhu izidakamizwa has impendulo engeyinhle. Odokotela baye babika ukuthi uyakwazi ukubangela eminingi engemihle. Lesi sidakamizwa ikhuthaza kwesisindo, kodwa futhi eziyingozi kakhulu esikhumbeni. Ngaphezu kwalokho, kukhona i uhlu umxhwele Izimo.