"Itomed": analogue, imfundo kanye impendulo

"Itomed" - nesidakamizwa esilutha ipheshana wokugaya ukudla. I nomuthi kuthuthukisa motility emathunjini bese ithoni. Umuthi has a action strong anti-emetic.

Izingxenye zomuthi, ifomu ukukhululwa

Ukulungiswa senziwa itopride isisekelo, etholakala ifomu tablet. Isikali lomcebo asebenzayo iphilisi ngalinye kuba mg 50. Izibhebhe ayatholakala amaphakethe of izingcezu 40 no-100. izingxenye Asizayo ethulwa acid Silicon anhydrous, hypromellose, i-lactose, makragolom 6000, corn isitashi, magnesium stearate, wax carnauba, ama-titanium dioxide futhi carmellose. Ezimweni lapho umuntu kungahlali "Itomed", amalungiselelo efanayo akhethiwe onguchwepheshe, kodwa yenziwe ngohlobo oluhlukile.

isinyathelo kwemithi, pharmacokinetics

Imithi kungokwalabo antacid izindlela esigubuzele. Umuthi futhi ine umphumela anti-isilonda, akashintshi ezingeni gastrin. Okhulisa GI motility kungenxa umbango we Dopamine D2-receptor futhi zivimbele acetylcholinesterase.

Imithi ikhuthaza ukukhululwa acetylcholine, ivikela ke ekubhujisweni. isinyathelo Antiemetic eba ngenxa nokuxhumana D2-Dopamine receptor, okuyinto zitholakala ezindaweni inhlamvu.

Ngemuva kokufaka isicelo amaphilisi lifinyelele ukucindezelwa umthamo-engaphansi ukuhlanza, okuyinto senziwa ukubonakala "apomorphine".

Ukusebenzisa izidakamizwa kuye kwaba nomphumela omuhle ngomsebenzi elingenhla pheshana emathunjini, ngokusebenzisa leli thuluzi ngesivinini zokuthutha umphakathi ngokusebenzisa esiswini, ngokuba inqubo emisiwe bethulula. Kusetshenziswe esikhundleni 'Itomed "analogue nomphumela ofanayo.

Absorption we nomuthi ku pheshana emathunjini kwenzeka ngokushesha, bioavailability cishe 60%. Ukuze lokuhlushwa izidakamizwa egazini baba esiphezulu, kudingeka imizuzu engu-30 kuya ku-45. Ukubuthelela izimali emzimbeni incane. amaprotheni Ukuxhumana: albumin - 96% alpha acid glycoprotein --15%.

Imithi is kahle kwasakazwa kwezicubu, lingena emathunjini amancane, esiswini, izindlala adrenal, isibindi, izinso. "Itomed" itholakala ukubunjwa ubisi lwebele, inani elincane butholakala emgogodleni kanye nobuchopho. izinqubo umzimba zenzeka esibindini, izinso ukuboniswa ikhambi, ukususwa esinqunyiwe kwenzeka emahoreni ayisithupha, khashana Trimethylaminuria.

Izimpawu, contraindications

"Itomed" analogs babelwa uma kudingeka ekwelapheni nonulcer dyspepsia, ephelezelwa ezingamahlalakhona kolwelwesi ukuma. Umuthi kuboniswa ngenxa distension besisu, ukucanuzela kwenhliziyo, ukuhlanza etholakalayo nge ukuthuthukiswa, isilungulela ubuhlungu esiswini. Uma iziguli ukungakhululeki besisu, ikakhulukazi esifundeni epigastric, wamisa "Itomed", injongo yayo kungenzeka noma ukuzincisha.

Tablets ungathathi hypersensitivity kuya izingxenye zabo, lapho ukopha emathunjini bese esiswini. Izimo lihlanganise malabsorption zikashukela-galactose, ukungezwani ne-lactose, ukuntuleka lactase. Ungasebenzisi izidakamizwa ezinganeni ezingaphansi kweminyaka eyishumi nesithupha ubudala, wakhulelwa futhi abesifazane lactating. Analogs "Itomeda" kungenziwa ifaniswe ne perforations ka ipheshana wokugaya ukudla bese isimiso lokukhanda.

izimo ezithile zokwelashwa edingekayo uma kuhlinzwa iziguli ezifuna ukuthatha m-cholinomimetics futhi inhibitor holinoesterazy, iziguli esezikhulile iziyaluyalu izinso kanye esibindini.

Ukusetshenziswa imithi, umthamo

Umuthi ukuthatha nsuku zonke kuze kube ukusetshenziswa ukudla at umthamo we-150 mg, isb kudinga amaphilisi kathathu, 50 mg isikhathi. umthamo Asebekhulile encishisiwe. Ezimweni lapho abakwazi ukuthatha iphilisi ngesikhathi, ukuthi kuqhutshekwe nokusebenzisa izimali kumele kwenziwe, abagcina ngezikhawu alinganayo. Awukwazi kabili umthamo.

side effects

side effects kungenzeka ngemuva kokuthola izindlela "Itomed". analogs Guide uncoma lokuqoka, uma angahambisani izidakamizwa esigulini. ukusabela engathandeki kungase ukuthuthukisa i-kokudla, onovalo endocrine. Ezinye iziguli ziba komzimba, ukushintsha okwesikhashana izinkomba laboratory. ukuphazamiseka okungaba khona kuya omzimba futhi zokuzala. Zingaphazamisa umzimba Izilonda zenzeka. Kukhona imiphumela emibi zihlanganisa izinguquko ohlelweni hematopoietic.

Overdosing siqedwa ngu lavage esiswini kanye nokuqaliswa yokwelapha lingaze. Ezimweni ezinjalo, okunye ukwelashwa angabelwa esikhundleni kusho "Itomed" nozakwabo.

Izixwayiso

Uma isiguli kutholakala izimpawu gynecomastia futhi galactorrhea, ukwelashwa ukumisa okwesikhashana noma ulithumele kwenye izidakamizwa. Sebenzisa "Itomeda" ekwelapheni isifo sokusha biliary (primary) kungaholela odlulayo isifo sokusha decompensated iyisimo ubalekela angesabi emva izidakamizwa zokuqaleka. Worth isikhathi bangayeki umsebenzi obalulekile, lapho isidingo ukwandisa ukunakwa lengqondo okusheshayo ukusabela ngesikhatsi ukwelashwa ngemithi "Itomed". Analogs, esikhundleni zikhethwa kanye onguchwepheshe, uma kunesidingo.

"Itomed" imiphumela ukumuncwa ngokushesha kakhudlwana ezinye izidakamizwa. Umthelela izidakamizwa is hhayi phansi ngenxa kokuthola izindlela, okuyinto isenzo sibhekiswe ekunciphiseni asidi esiswini. Effect lingaphansi evelele, ngenkathi uhlelo lokusebenza le-nomuthi nge m-holinoblokatorami, ukulungiswa lihambisana inhibitor holineserazy, m-holinomimetikami namandla umphumela ukuthatha amaphilisi "Itomed". Analogs kungase ukuzibonakalisa ehlukile ezimweni ezifanayo.

Izibuyekezo Analogs

Lapho kubalulekile ukuba esikhundleni izidakamizwa, le nkinga okuxoxwa nge onguchwepheshe. Ngokuvamile, esikhundleni lodokotela ukunquma "itopride" kanye nokwelashwa ukuziphatha nge "Itopra" amalungiselelo noma "Ganaton". Lezi analogs "Itomeda" yakhiwa isithako efanayo esebenzayo.

Ikhishwe futhi esikhundleni yasekhaya imithi. Kukhona namathuluzi "Itomed" analogue (Russia), ezifana "Tseruglan", "Gastrika-GF".

Naphezu kweqiniso lokuthi "Itomedom" iziguli ziphathwa isikhathi eside, ubuyekeze uhlelo lwayo lokusebenza akwanele. Ngokuvamile ngokuthatha izidakamizwa ngaphakathi nelesithupha amaviki uhola okuphambili indaba yokuqeda ukubuyisa, isilungulela kwehlisa kuholela ukunyamalala phansi esiswini futhi ukuvela iphango. Iziguli uthole umuthi ngoba ukuqunjelwa kanye namafomu ezingamahlalakhona. Izibuyekezo kubonisa tolerability ezinhle izidakamizwa futhi ayikho imicimbi sina ezingezinhle. Ngokuvamile eba nesifo sohudo, kukhona ikhanda futhi ubuhlungu esiswini. Izibuyekezo ukukhombisa ukuthi izidakamizwa kungaholela amenorrhea. Nokho, bonke ngamunye futhi isenzo "Itomeda" zingabi, ukuthi kwakungekho nemiphumela emibi ngendlela efanayo, ukwelashwa kufanele udokotela.