Isidakamizwa 'Retinol acetate'. Imiyalo

Isidakamizwa "I-retinol acetate" imfundo ibhekisela eqenjini le-pharmacotherapeutic lamavithamini. Ikhambi lisiza ukugcwalisa ukungabi khona kwevithamini A.

Amathebulethi kanye nesisombululo se- "Retinol acetate" sikhuthaza ukuqaliswa kwezinqubo ze-redox, zibandakanye ekusimeni kwe-metabolism, ukudala izimo ezihle zokuhlanganiswa kwe-ATP. Lesi sidakamizwa sishukumisa inqubo ye-epithelization, ivimbela i-hyperkeratosis (ukwanda ngokweqile kwe-epithelium). Ngaphezu kwalokho, i-ejenti igcizelela umsebenzi wezithukuthuku nokuzikhukhumeza.

Uma ukhulunywe ngomlomo, umuthi cishe ususwe ngokuphelele ohlelweni lokugaya. Imikhiqizo ye-metabolism (i-retinoic acid, i- retinal, i-retinol ne-retinyl palmitate) isatshalaliswa ngezitho nezingxube ezingenalutho. Ukuhlushwa okuphezulu kakhulu kubonakala ku-retina nesibindi. Isamba esincane sitholakala ezigulini eziyingozi, ibele (lactating), amaphaphu, izitolo ezinamafutha, inhliziyo, izinso.

Ithuluzi elithi "Retinol acetate" imfundo lincoma ukungenwa kwamavithamini kanye ne-hypovitaminosis A, izifo ezithathelwanayo (izifo zengculazi, i-bronchitis, i-tracheitis, i-dysentery, isishubhu). Isidakamizwa siboniswa izifo zesikhumba (ezinye izinhlobo ze-eczema, i-pyoderma, i-psoriasis, ichthyosis, i-hyperkeratosis, isifo sofuba lesikhumba, amanxeba, ama-frostbite, ukushisa, izinqubo ezishisayo nokuvuvukala). Ithuluzi elithi "Retinol acetate" imfundo iphakamisa izifo ze-ophthalmic (conjunctivitis, izilonda ze-eczematous zamajwabu amehlo, i-keratomalacia, i-xerophthalmia, i-hemostalopia, i- retinitis ye-pigment). Izinkomba zihlanganisa izifo zokuphefumula eziyingozi, ukungondleki, iziphuzo ezincane, izifo ze-bronchopulmonary ezingapheli, izilonda ezivuthayo nezilonda ezilonda emathunjini omzimba, i-leukemia, izicubu ze-epithelial, i-cirrhosis yesibindi, ukukhathazeka.

Ukulungiswa "kwe-Retinol acetate" kunconywa ukuthi kusetshenziswe ngaphansi kokuqondiswa udokotela. Ikhambi kufanele lithathwe ngemuva kokudla kusihlwa ebusuku noma ekuseni.

Nge-avitaminosis ye-degrees ephakathi nendawo emnene, umthamo wokwelapha unqunywe kanje: kubantu abadala - ngosuku kuze kube ngu-33 000 i-IU, nge-pigment retinitis, i-xerophthalmia, i-hemeralopia - 50 000 - 100 000 IU. Isilinganiso sezingane sisethwe ngokuhambisana nonyaka kusuka ku 1000 kuya ku-5000 IU ngosuku.

Uma isikhumba se-pathologies esikhulile siyakunconywa ukuba sibe ngu-50 -100 ama-IU, abantwana - kusuka ku-5 kuya ku-20 000 IU ngosuku.

Isilinganiso somthamo owodwa akufanele sidlulele ama-50 IU (abantu abadala) no-5 000 IU (ezinganeni). Ngosuku aluvumelekile ukuthatha abantu abangaphezu kwezingu-100 ze-UU kubantu abadala kanye no-20 000 IU ezinganeni.

Uma usebenzisa lesi sidakamizwa "i-Retinol acetate" emithweni ephakeme, kukhona umphumela we-teratogenic, ophikelela ngemva kokuhoxiswa kwawo. Kulesi sixhumanisi, kungenzeka ukuthi uhlele ukukhulelwa kuphela ezinyangeni eziyisithupha kuya kweziyishumi nambili emva kokuphela kohlelo lwezokwelapha.

Ngokusetshenziswa kwesidakamizwa "i-retinol acetate" imiphumela embi ingenzeka. Ukulala, umkhuhlane, ukuhlanza, ukuphefumula, isicashu, insizi ingase ivele. Kwezinye izimo, kukhona ukwephulwa kwemali, ukunyuka komlenze, ukukhishwa kwesikhumba. Uma uthatha amanani aphakeme, i-hypervitaminosis cishe. Isidakamizwa "I-Retinol acetate" ezinganeni zingabangela ukwanda komfutho we-cerebrospinal fluid (ezinganeni zingabonakaliswa ukuvuthwa kwe-fontanel ne-hydrocephalus), ihlamba esikhumbeni, ukuhlanza, ukujuluka, mhlawumbe ukukhuphuka kwezinga lokushisa. Ezimweni ezingavamile, ngosuku lokuqala lwezokwelashwa, kungenzeka kube khona ukuqhuma okwebala emakhaleni. Lokhu kudinga ukukhanselwa kwezimali.

Njengoba kunciphisa umthamo noma ukuhoxiswa okwesikhashana kwesidakamizwa se-retinol acetate, imiphumela emibi ivame ukuqedwa yedwa.

Isidakamizwa siyaphikisana nokukhulelwa (ku-trimester yokuqala yokubeletha), ne-cholelithiasis, i-hypersensitivity, i-pancreatitis engapheli.

Isidakamizwa "I-retinol acetate" (ukubuyekezwa kwabanye abantu kubonisa lokhu) kungasetshenziselwa imithi yezilwane. Ngakho-ke, lesi sidakamizwa sisebenza kahle kwi-hyperkeratosis ezilwaneni.

Ungathathi isidakamizwa "i-Retinol acetate" ngaphandle kokubonisana nochwepheshe. Ngaphambi kokusebenzisa, kufanele ufunde isichasiselo.