Isidakamizwa esithi "Nice" (amaphilisi). Imiyalo yokusetshenziswa

I-Naise ikhiqizwa ama-pharmacists aseNdiya, yathandwa ezweni lethu ngenxa yamacala awo amaningi, futhi eyona eyinhloko ikhono lokunciphisa ngokushesha noma ukucindezela ngokuphelele isifo sobuhlungu bomsuka ohluke kakhulu. Isidakamizwa esithi "Nice" (amaphilisi) okusetshenziselwa ukusetshenziswa sibhekisela kuma-anti-inflammatory non-steroidal agents ezikwazi ukubonisa imiphumela ye-analgesic, antipyretic ne-anti-inflammatory.

I-pharmacokinetics yalesi sidakamizwa ngemiyalelo ichazwa kanje:

Ngemuva kokungenwa, lo muthi ubambe kahle. Njengoba egazini lijikeleza esimweni esithinta amaprotheni egazi, uma sisetshenziswa ngokuhlanganyela neminye imithi, i-nimesulide iyakwazi ukuyikhipha ezibophweni ngamaprotheni futhi, ngokufanele, ukwandisa ukuhlushwa kwamaqenjini abo mahhala egazini. Iqiniso lokuhlanganyela nokudla kokudla kwezidakamizwa elithi "NICE" (amaphilisi) okusetshenziselwa ukusetshenziswa ichaza njengento eyenza ukunciphisa umuthi osebenzayo, kodwa akuthinteki nakancane izinga lokumuncwa kwalo.

Izinkomba zokusetshenziswa kwazo zikhona ngale ndlela: i-myalgia, i-etiology ehlukahlukene kunazo zonke ye-arthritis, i-arthralgia, i-genesis ehlukahlukene ye-fever, i-algodismenorea, i-bursitis, ikhanda nezinhlungu zinozinyo, i-tendonitis, ubuhlungu bokuthutha nokuthunyelwa ngemuva, i-osteoarthrosis.

Ukuphikisana kwezidakamizwa "I-NICE" (amaphilisi) imiyalelo yokusebenzisa izingcingo ukuhluleka kwezinso nesibindi, ukuzwela okwedlulele ezingxenyeni zomuthi (ikakhulukazi i-nimesulide), izifo zendlela yokugaya umzimba, ukuphuma kwangaphakathi (ikakhulukazi emgodini wokugaya), ukukhulelwa, isikhathi sokuncelisa. Futhi ukuphikisana kuneminyaka yobudala abangaphansi kweshumi nambili. Ngokuqapha, i-"Nice" (amaphilisi) ukulungiselela ukukhuthaza ukuthi iziguli ezine-hypertension, isifo sikashukela, uhlobo lwe-II, ukuhluleka kwenhliziyo kufanele kubekiwe.

Ukuze ulungiselele "NICE" (amathebulethi), ukubunjwa emfundisweni kunikezwa ngalokhu okulandelayo: Into esebenzayo enkulu ye-nimesulide ingama-milligram ayikhulu, izinto ezisizayo.

Amaphilisi a "Nice" athathwa ngomlomo kabili ngosuku, ngaphambi kokudla, enevolumu eyanele yamanzi. Uma isiguli sibhekene ne-pathology ye-digestive tract, i-"Nice" (amaphilisi) ukulungiselela ilungiswa ukusetshenziswa ngemva kokudla noma ekupheleni kokuphathwa kwayo. I-dose evunyelwe kakhulu ngosuku ngalunye ngama-milligram ayikhulu.

Kuzingane ezingaphezu kweminyaka eyishumi nesishiyagalolunye nesisindo somzimba esingaphezu kwamakhilogremu amane, unqunywe ngokusekelwe kulokhu kubalwa: i-milligram eyodwa nengxenye kilogram yesisindo somzimba. Kule minyaka yobudala nesigaba sesisindo, ukutholakala okuphezulu kwesidakamizwa kumthamo ongadluli ama-milligram amahlanu kilogram ngosuku ngalunye kuvunyelwe.

Kubantwana abaneminyaka engaphezu kweyishumi nambili, kodwa ngesisindo somzimba esingasifiki kilogram ezingamashumi amane, i-"Nice" (amaphilisi) imfundo yokulungiselela imfundo ikhuthaza ukusebenzisa ama-milligram kabili ngosuku. Isikhathi sokwelashwa izinsuku eziyishumi.

Imiphumela emibi, engayinika imithi "Nice", imfundo kuye ibala okulandelayo:

Ezingxenyeni zendlela yokugaya ukudla, isicanucanu, isifo sohudo, ukuhlanza, ukuphuza inhliziyo, kungenzeka isibindi, ukwanda komsebenzi we-transaminase, isifo sofuba esibhedlela, i-mucosa yegciwane lokugaya ingase isilonda. Kusukela eceleni kwesimiso sezinzwa, ukuphathwa ikhanda nokuzizwa ngezinye izikhathi kubonakala. Esikhathini senqubo yokujikeleza - ukuthuthukiswa kwe-anemia, i-agranulocytosis, i-thrombocytopenia, i-leukopenia, ukwanda esikhathini esiyimfuneko esidingekayo ukuyeka ukuphuma kwegazi, i-hematuria. Futhi, ukusabela okwenziwe okwehlukile kokuqina okungafani kungase kuthuthuke, ukugcinwa kwamanzi emzimbeni.