Imijovo "Ketorolac": yokusetshenziswa, nozakwabo yangempela

"Musa akhononde ubuhlungu -. Yilokho umuthi best" Lawa amazwi Omar Khayyam. Kungenzeka ukuthi indlela okuyiyo, uma kuziwa yokuhlushwa ngokwengqondo. Uma sikhuluma izifo zomzimba, ukukhononda akudingekile, kubalulekile ukusiza emzimbeni wakho. Omunye amaphilisi ezinhlungu sasivumela ngempumelelo manje ezinkandini "Ketorolac". Iziyalezo yokusetshenziswa aqukethe ulwazi oluphelele kakhulu imithi.

Ukwakheka kanye pharmacodynamics

Ubulunga be-izidakamizwa - non-steroidal izidakamizwa eqeda ukuvuvukala. Lisuselwa pyrrolizine-carboxylic acid. The main ingxenye esebenzayo - tromethamine ketorolac (1 ml isixazululo iqukethe 30 mg) isebenze njengomxhumanisi izinto asizayo ezifana disodium usawoti, futhi i-sodium chloride, ethylenediaminetetraacetic acid, ETHYL utshwala, kuyalungiswa, tromethamine.

Painkillers "Ketorolac" umbukiso nomphumela evelele analgesic. Isici salokhu izidakamizwa njengoba umphumela anti-inflammatory nomphumela antipyretic ngokulinganisela.

lo mshini umthelela kusekelwe ukucindezelwa womsebenzi Cox. Lona enzyme eyinhloko arachidonic acid, okuyinto yena, kuyinto eyandulela ka prostaglandins, okuyinto ukudlala "ivayolini" ku pathogenesis ukuvuvukala, ubuhlungu, kanye nemfiva.

"Ketorolac" (isibhamu) libuyekeza abasebenzi bezokwelapha ngezikhwepha analgesic imiphumela kubhekwe ifaniswe morphine futhi kakhulu kokwalabo nezinye ama-NSAID.

izinkomba

Le ndawo eyinhloko yohlelo zomuthi - syndromes ubuhlungu nge imnene ezinzima. Imithi esetshenziselwa therapy okunezimpawu ukuba inciphisa ubuhlungu nokuvuvukala ngesikhathi ukulaliswa esibhedlela. On ukuqhubekela phambili kwesifo awukho umphumela.

Nikeza leli thuluzi ezimeni post-partum nobuhlungu post-op. Ngokuphumelelayo zokwelapha lezi imijovo ubuhlungu bamalunga cuphuluza ukulimala nemisipha ziklebhukile, ubuhlungu kwamazinyo.

Futhi, imijovo "Ketorolac" yokusetshenziswa Kunconywa for ekwelapheni Ukwenyela, amagciwane, imisipha ubuhlungu futhi ubuhlungu emuva. Linqume izidakamizwa umdlavuza, myalgia, arthralgia, neuralgia.

Izimo ukusetshenziswa

Akumele usebenzise izidakamizwa ekwelapheni yalezo ziguli usulungise hypersensitivity kunoma yezingxenye. Wokwalelwa njengoba khona "aspirin triad" futhi hypovolemia (izizathu okuyinto wayithukuthelisa isifo ayibalulekile). Futhi, "Ketorolac" (amaphilisi kanye imijovo) akazange liqoke labo yini erosive kanye izilonda emathunjini ipheshana emathunjini ku esigabeni oyingozi.

Akumele usebenzise lezi imijovo ukwelapha labo abaphethwe hemophilia, anticoagulation futhi athambekele ukopha noma ingozi eliphezulu yentuthuko yabo.

Futhi contraindication kuba phambi esingamahlalakhona ezinzima kwezinso noma hepatic.

Hhayi wabonisa ukusetshenziswa "Ketorolac" ngokushesha ngemva yenhliziyo ukuhlinzwa Umthambo dlula, phakathi kwe-yokuthathu yesithathu yokukhulelwa, ngesikhathi sokubeletha lactation. Contraindicated imijovo izingane kuze kube iminyaka engu-16.

Isicelo kanye umthamo

I umthamo umjovo is akhethiwe ngamunye ngokusekelwe ebucayini ubuhlungu. Imijovo "Ketorolac" yokusetshenziswa ivumela entry / m / e. indlela esicutshini, lemali kwesikhathi esisodwa kwama-10 kuya ku-30 mg. Isikhawu phakathi ukwelashwa akumele ibe emahora langaphasi kulangu-4-6. Izinga esiphezulu yokwelashwa - kwezinsuku 5.

I umthamo wansuku zonke we / m 90 mg. Nokho, i-iziguli nesisindo 50 kg, kulabo abaphethwe kahle izinso umsebenzi futhi kwezinye iziguli abaneminyaka engama 65, umthamo kumele singeqi inani mg 60.

Ukuze uthuthukise umphumela analgesic ngokuvamile ebekiwe ukuthola imijovo kanye amaphilisi "Ketorolac" in the eziyinkimbinkimbi.

Yokukhulelwa kanye lactation: Ingabe ukusetshenziswa kuvunyelwe "Ketorolac"?

Imijovo "Ketorolac" imfundo on isicelo sivimbela ukusetshenziswa ekwelapheni kwabesifazane abakhulelwe. Ukusetshenziswa kwalesi imithi kungenzeka ngenxa yezizathu zempilo, lapho kulindeleke nomphumela omuhle ngoba unina kude okungaba yingozi ingane kuphela.

Uma nganoma isiphi isizathu kukhona isidingo sokwelashwa "Ketorolac" esikhathini lactation, kubalulekile ukuxoxa nodokotela umbuzo yokwenqaba ukuncelisa.

Ochwepheshe bezokwelapha musa batusa futhi sisebenzise "Ketorolac" ngoba premeditatsii asekelayo izinzwa kanye analgesia esabeletha, njengoba lokhu izidakamizwa uyakwazi ukuba zinde inkambo esigabeni sokuqala zomsebenzi. Ngaphezu kwalokho, "Ketorolac" kungaba nomphumela ezicindezelayo ezikuyi-lesizalo contractility kwegazi wengane.

imiphumela Okungenzeka engathandeki

nemiphumela emibi ezinkandini "ketorolac" okuyinto isicelo iye echazwe ngenhla, futhi ahlukahlukene ngempela futhi kungaba ilandelwe izinhlelo ezihlukahlukene. GI kungaba ngokuvamile aphendule ukuthuthukiswa sohudo kanye ukubukeka izimpawu gastralgia. Ngaphansi ngokuvamile, ungakwazi ukuzwa ukuqunjelwa, ukuhlanza, ukubuyisa, ukuthuthukiswa izilonda emathunjini.

uhlelo urinary iyaphendula Nokho ukuba "Ketorolac" awavamile, futhi ungezwa mayelana hematuria, iqolo, edema, nephritis futhi imvelaphi kwezinso.

Libuye ngempela ezingavamile ekuphenduleni imijovo athi angama umgudu wokuphefumula (bronchospasm, rhinitis, ukuvuvukala amaphaphu amalaka) futhi izinzwa (ongaboni Ukuwohloka bezibona sokuzwa, enkeneneza ezindlebeni).

Iziguli ngokuvamile bathi mayelana impendulo sezinzwa uhlelo ukuze "Ketorolac", owabonakaliswa ukozela, isiyezi, ubuhlungu bekhanda. Ngaphansi ngokuvamile, ungezwa ngezimpawu ze-aseptic meningitis, futhi hyperactivity, ukubukeka sengqondo futhi babone izinto ezingekho.

Ngezikhathi ezithile kukhona ulwazi mayelana nemiphumela engathandeki esimiso senhliziyo nemithambo yegazi (kwenyuke blood pressure), uhlelo hematopoietic (leukopenia, anaemia), uhlelo hemostatic (ukopha - acinene, rectal, nasezinkingeni ezilandela ngemva kokuhlinzwa).

Iziguli ngokuvamile bathi mayelana nokubonakala edema ubuso, imilenze, amaqakala nezinzwane, isisindo somzimba, ukujuluka anda.

Ukweqiwa ngokweqile

Symptomatology overdosing le nomuthi "Ketorolac" (venipuncture noma intramuscularly owawasho) sivezwe ikakhulu emizweni zobuhlungu esiswini, e isicanucanu nokuhlanza. Futhi, iziguli kanye abasebenzi bezempilo ukuphakamisa kungenzeka izilonda erosive-ulcerous yokusetshenziswa pheshana emathunjini, ukuphazamiseka ukusebenza izinso, lactic umzimba (eba ngenxa yokuzuza emisipheni ukudla esidi, ukungabi ngibopha noma nokucekelwa).

Ukwelashwa ezimweni ezinjalo siyefana futhi ihlose ukugcina imisebenzi ebalulekile emzimbeni. abalulekile umphumela hemodialysis ngeke.

Yini oyibhekayo?

Ngaphambi kokuqala ukwelashwa, "Ketorolac", kubalulekile ukuthola ukuthi ingabe esake amacala komzimba nemithi ethile noma ezinye ama-NSAID eqoshiwe. Umjovo wokuqala desirably kwenziwe khona udokotela (ukuvimbela yokungezwani komzimba).

Uma kunesidingo, ungakwazi ukusebenzisa "Ketorolac" (imijovo) lihambisana analgesics kwezidakamizwa. Iziguli kwezinso ku igazi ekunqandeni, "Ketorolac" zidinga isimo ukusetshenziswa kuphela nokuqapha njalo platelet ibala. A inkinga esheshayo ikakhulukazi lena kubantu abaye ngahlinzwa futhi zidinga ngokucophelela ukulawula hemostasis.

Abantu abanezifo ezingamahlalakhona futhi ubuhlungu ukwanda esikhathini yokwelapha kungabangela ukuthuthukiswa yezinkinga izidakamizwa.

Phakathi ukwelashwa "Ketorolac" kubalulekile ukuba siqaphele ekuphathweni umgwaqo futhi ugweme izinhlobo ezinobungozi zomsebenzi ezihlobene ne bagxila nesivinini anda lengqondo ukusabela.

Ukuxhumana nezinye izidakamizwa

Kanyekanye ithola "Ketorolac" ne-paracetamol kwandisa nephrotoxicity kuqala. ngokuvamile iziguli unesithakazelo umbuzo ukuthi kungenzeka ukuba sihlanganise isibhamu "Dikloberl" futhi "Ketorolac". Impendulo ingu-cha: inhlanganisela "Ketorolac" nanoma iyiphi enye NSAID kwandisa amathuba izilonda asathuthuka futhi mucosa emathunjini ingavuthi imbangela ukopha emathunjini.

ukusetshenziswa Parallel nge anticoagulants, izindlela zokwelapha antiplatelet, futhi acetylsalicylic valproic acid, cephalosporins kukhulisa ematfuba ukopha.

"Ketorolac" kunciphisa ukusebenza izidakamizwa ukuthi kunciphise umfutho wegazi, futhi isisu. "Methotrexate" kwandisa hepato-futhi nephrotoxicity "Ketorolac". Umthelela elifanayo kuyoba parallel yokwamukela noma yimuphi izidakamizwa nephrotoxic ngaphezulu. Izidakamizwa ukuthi uvimbele uketshezi ijabulise, ukunciphisa imvume "Ketorolac" futhi ngaleyo ndlela andise lokuhlushwa yayo plasma.

Ngaphezu kwalokho, imijovo "Ketorolac" ukwandisa nekusebenta analgesic izidakamizwa hlobo.

Imithi - analogue nama lebanga lentengo

Abaningana impela zinemiphumela efanayo emzimbeni imithi womuntu kuyatholakala at izidakamizwa "Ketorolac" (imijovo). Iziyalezo ukusetshenziswa analogs uchaza yefomu ngamunye ukukhululwa, okungukuthi. E. Ngoba umjovo, kanye amaphilisi. Ungakwazi ucacise kunazo owaziwa futhi ethandwa umthengi izixazululo umjovo imithi efana "Ketanov", "Ketalgin", "Ketorol", "Ketofril", "Ketorolac-Eksmo", "Ketorolac-Tromethamine", "Dolak", "Dolomin" "Toradol."

Ngokuphathelene intengo, izindleko iyunithi 10 vials ngalunye ngesikhathi umthamo 30 mg / ml ububanzi ruble 63 kuya 144.

Izibuyekezo umthengi

abathengi abaningi ziyaneliswa kakhulu ine umphumela. imiphumela emihle babonakala kweziningi ubuhlungu ongakhetha ke uncoma ngaphansi kwazo ekwelashweni kusho "Ketorolac" imfundo manual. Imijovo libuyekeza iziguli zesifazane kuchazwe kahle kakhulu ubuhlungu esikhathini. Ngokuvamile, imijovo yasetshenziswa nobuhlungu yamazinyo, nokuphathwa ubuhlungu inqubo ukunyakaza amatshe e-izinso futhi esikhathini postoperative, futhi kwezinye izimo eziningi.

Umphumela omuhle izidakamizwa kakhulu ekudambiseni isimo iziguli, Nokho, futhi Imithelela eseceleni yayingavamile endaweni ukuba. Ngakho, iqembu ahlukene abantu ukhuluma ngani ukubukeka kwesikhumba ukusabela ubuhlungu besisu. Nokho, lokhu akusho kunganciphisa ukusebenza yayo okusezingeni eliphezulu njengoba painkiller kanye ejenti eqeda ukuvuvukala.

Ngaphezu kwalokho osekushiwo, iziguli weneliseka intengo imijovo "Ketorolac", okuyinto aphansi ukwedlula izindleko cishe zonke ontanga yayo.

ubufakazi uchwepheshe

Ngokusho odokotela mayelana izidakamizwa "Ketorolac" futhi babe izinhlangothi zombili emihle nemibi. Njengoba ingxenye enkulu yomsebenzi ochwepheshe bakholelwa ukuthi uma ulandela yonke izincomo, equkethe umuthi yawo "Ketorolac" imfundo (isibhamu), ke NSAID ukufeza yonke imisebenzi yayo kufanele nethonya elihle futhi akavumi ukuba ukuthuthukiswa izigigaba ezingezinhle.

Umuthi akusho ukungena cerebrospinal fluid, njengoba izidakamizwa kungagcini - kuphela endaweni ukuvuvukala. habituation umphumela futhi lingekho.

Ngokuqondene impendulo engeyinhle kusukela ochwepheshe, kungashiwo ukuthi iqembu elihlukile odokotela ukholelwa ukuthi "Ketorolac" unethonya ababuthakathaka eqeda ukuvuvukala. Futhi, odokotela bathi nomthelela omubi kwamanyikwe (sikashukela sicasulwa) futhi ukusebenza nezinso.

Ngokuvamile kungashiwo ukuthi iziqondiso nokulandela izincomo udokotela okwelaphayo izonikeza umphumela omuhle kakhulu ukusetshenziswa imijovo "Ketorolac" ngaphandle ingozi izenzakalo sina ezingezinhle.