Hypogonadism ezingabantu: Izimpawu kanye Ukwelashwa

ukusebenza okuphelele umzimba womuntu ayikwazi wacabanga ngaphandle ekusebenzeni kahle nezindlala ocansini, ekukhiqizweni kwama-hormone. Noma yimuphi ukwehluleka kulesi simiso kuhilelani ukuvela izifo ukuphathwa kwabathintwayo. Dyslipidemia, isifo sokuqina kwemithambo yegazi, ukukhuluphala, ubuchopho ischemia - lokhu akulona lonke uhlu yezinkinga kungenzeka. Ngo yezokwelapha izincwadi ezitholakala izincazelo eziningi ukuhlukumeza okunjalo. Ngokwesibonelo, wamasende ukuntula androgen noma esingamahlalakhona. Nokho, phakathi kwabo, lo athembeke kakhulu inembe kunazo kubhekwa igama elithi "hypogonadism" ezingabantu. Ukuthi lesi simo senzeka kusho, nganoma yisiphi isizathu kuphakama noma ngabe ingelapheka - mibuzo ethulwa izimpendulo enemininingwane esihlokweni lanamuhla.

Incazelo emfushane lesi sifo

Hypogonadism - isifo elinesimo obusebenzayo ukuntula ubulili nezindlala. Laba bameleli be-wobulili namandla ethulwa isende kwesokunxele nakwesokudla. Nature uye walungiselela ngokukhethekile abhanqiwe ke inombolo yabo. Wamasende izicubu luvelo izingozi ezahlukene kwemvelo. Endabeni ka ukulahlekelwa amakhono ukusebenza emzimbeni Kufanele ube uhlobo Reserve. ikhono okuzivuselela we testes kuyinto ngempela nesizotha.

injongo yabo eyinhloko - ukuze ukukhiqizwa kabusha. Ukuntuleka kokukhulumisana ikhono ekhiqiza isidoda phuca emzimbeni amakhono besilisa zokuzala. Izindlela komgomo ezinjalo wabeka lapho besanda kuqala lomjikelezo zokuzala. Ngakho-ke, ukungazali, ukuthuthukisa kule ngemuva, uyingozi kakhulu. Buyisela umsebenzi amaseli angavamile kwezicubu wamasende cishe kungenakwenzeka.

Hypogonadism ezingabantu libhekene izici ezilandelayo:

• ukuncipha kancane kancane izinga lama-hormone ocansini;
• nokwehlisa izici qualitative ambalwa of isidoda;
• hypoplasia we umthondo;
• iziyaluyalu hormone wonke umzimba.

Ngokwezibalo, lesi sifo ka hypogonadism ezingabantu kwenzeka 1% labantu emhlabeni. Nokho, lolu lwazi lwesikhashana, njengoba ziyabhekelelwa kuphela amacala bhalisiwe zokugula. Ukwelashwa ngempela eyenziwa ngaphansi kweso endocrinology futhi andrologist. Elivame ukusetshenziswa kakhulu yokwelapha i-hormone. Uma wabelwe ukwehluleka nokuhlinzwa plastic kanye emkhakheni wezitho zokwenziwa izitho kwesimiso sokuzala.

Ziyini izimbangela eziyinhloko zalokhu lesi sifo

Ukuthuthukiswa inqubo sokugembula senzeka ngenxa wokunciphisa inani lama-hormone ekhiqizwa noma sokuphazamiseka biosynthesis. Ngu izici etiological lesi sifo zihlanganisa:

• kombungu esizalweni kubangelwa ushintsho isakhiwo wamasende kanye / noma tubules seminiferous;
• ithonya umzimba ubuthi omama esizayo (utshwala, i-nicotine, izidakamizwa);
• ibhekane ngemisebe noma imiphumela emibi yokwelashwa ngamakhemikhali;
• ukusetshenziswa kwesikhathi eside hormone, imithi elwa namagciwane,
• izifo Lokudabuka ezithathelwanayo (orchitis ngemva isimungumungwana, mumps, vesicles);
• varicose emithanjeni we ngamasende;
• yokuhlala ezindaweni kwezimo zendawo ezimbi.

Izimbangela hypogonadism ezingabantu kubangele ukuma inqubo sokugembula. Ngamunye wabo libhekene indima ethile.

ukwephulwa izinhlobo

Kuye imbangela ecashile okuvela ukwehluleka gonads ihlukaniswe yobudala lokuqala, lesibili, nalokho okubizwa ngokuthi. Uyini umehluko? Ifomu eyinhloko lesi sifo ngenye ngokuthi zokugula wamasende. Kulokhu, lo esephule testes ukusebenza kwenzekani bedle izici zangaphandle ezimbi. hypogonadism yesibili ezingabantu lihlotshaniswa kwezinso kule scheme "pituitary-hypothalamus". Lolu hlelo ezivezwa hormone obhekene ukusebenza testes. Ubudala okufana lesi sifo ubhekwa uhlobo menopause besilisa. izimbangela zayo, odokotela abakwazi ukuchaza kuze kube yilolu suku.

Ukwahlukaniswa okulandelayo kusekelwe kulokho inkathi lapho kwakukhona lokugula. Ifomu embryonic libhekene ukubukeka inqubo sokugembula esikhathini yentuthuko lesizalo. Prepubertal kutholakala ukuthi uphethwe yini ngaphambi ukuthomba (iminyaka engaba ngu-14). samuntu Postpubertatnom sifo kwenzeka emva kokuphothulwa ukuthuthukiswa izici ngokobulili yesibili.

Sikhishwe inani androgens ekhiqizwa, ukuhlukanisa izinhlobo ezilandelayo isifo:

1. hypogonadism Hypergonadotrophic. In amadoda, lolu hlobo sifo kubonakala ngesimo ukubhujiswa kwezicubu wamasende wamasende. It kuhambisana umkhiqizo wawanda hormone pituitary. Ngezinye elifanayo izinkomba zesikhathi kwe-testosterone ziyancipha.
2. hypogonadism Hypogonadotropic. It libhekene zamagama kwehle of gonadotrophins. Lokhu kunciphisa inani testosterone kukhiqizwa.
3. hypogonadism Normogonadotropic. In amadoda, lolu hlobo inqubo sokugembula kuholela ukuphazamiseka emasendeni, kodwa ekukhiqizweni kwama-hormone pituitary kuyinto evamile. Lesi sifo ngokuvamile uhlanganiswa ukukhuluphala.

Kuye etiology kuyisiko ukuze ihlukanise izinhlobo azalwa naso, usezuze futhi idiopathic. Kulo mBhalo, imbangela eyinhloko isifo ayikaziwa.

hypogonadism eyinhloko

Lesi sifo kungaba kokubili abeyizuzile futhi azalwa nako. Ngokuvamile, zokugula kwenzeka utero. Boy ozalwa umthondo amancane i scrotum ampofu. Njengoba ukuqhubeka isithombe emitholampilo ye iyaguquguquka isifo. Entsheni abafana nge kutholakala ukuthi uphethwe yini Kutholwe ukhuluphele, gynecomastia ukubonakaliswa kokuqala degree eliphansi zonke iziboya emzimbeni.

Ngazuza hypogonadism oyinhloko amadoda ikhulela ukuvuvukala nezindlala kwesidoda ngaphansi iziyaluyalu ezilandelayo:

• orchitis;
• vesicles;
• epididymitis;
• mumps;
• inkukhu Pox.

Le ndlela lesi sifo ubhekwa ezivamile. Senzeka noyedwa kwabahlanu kwamanye amadoda ngaphambilini kutholakala ukuthi uphethwe yini nenzalo.

hypogonadism yesibili

hypogonadism yesibili kungenzeka azalwa naso noma bathenga. Esimweni sokuqala lesi sifo landulelwa ukuthuthukiswa uketshezi ezingafanele pituitary futhi hormone hypothalamic. It uvame ukuhambisana izifo ezibangelwa ufuzo:

• Prader syndrome - Willie;
• syndrome Maddock;
• syndrome Pasqualini.

Ifomu atholwe lesi sifo ngokuvamile kubangelwa ukuvuvukala meninges. Phakathi kwabo kukhona meningitis, arachnoiditis futhi encephalitis.

Izimpawu zesifo ezinganeni ezincane

Isithombe basemtholampilo inqubo sokugembula buvezwa yobudala lesiguli. Ukuthuthukiswa Its kusukela zisencane ngokuvamile uhambisana zimpawu ezilandelayo:

• Kwemikhuba ngesikhathi sokuthomba;
• evnuhoidizma ukubonakala izimpawu (ukukhula eziphakeme ngokwedlulele kuye, emahlombe encane, nemilenze eside);
• ukungabi imibimbi ku scrotum;
• ubukhulu encane umthondo;
• gynecomastia.

Ephambi kwezinduna okukodwa noma ngaphezulu izimpawu ezibalwe ngenhla kufanele ngokushesha uthintane isazi iphrofayli.

Izimpawu zalesi sifo indlela intsha eziphatha

Ukuthuthukiswa lesi sifo entsheni libhekene izimpawu ezifanayo, ukuthi prepubertal. isithombe Clinical kungaba umphelelisi kwehle libido nokukhuluphala ngokweqile. Ukuze ubone udokotela ngokuvamile Kutholwe hypoadrenalism futhi yegilo. Ngaphandle, abaprofethi bamanga iziguli intsha ngokucacile wabonakaliswa nokungathuthuki kohlelo kwemisipha.

Izimpawu zalesi sifo abadala

Hypogonadism ezingabantu abaneminyaka engama-30 ingaphansi evelele. Lesi sifo kuhambisana ukubukeka emphethweni amaningi fat emzimbeni. Skin ngokuhamba kwesikhathi kuyaqina yayo yangaphambili futhi omile. Kubonakala ukukhathala, lability ngokomzwelo, ukuthambekela ukucindezeleka. Ngeshwa, esibhedlela selashwe amadoda ezimweni ezehlukile. Ngokuvamile uma kuziwa ukungazali noma iziyaluyalu Erectile umsebenzi.

Lokhu ukungabi ukunakekela impilo yabo kungaholela emiphumeleni engathí sina. Inqubo sokugembula iqala ukusakaza hhayi kuphela kwi uhlelo zokuzala, kodwa kancane kancane kokuthuthela kwezitho nezicubu. Ukungabikho Usizo lwezempilo olunikezwa bungaholela ekukhubazekeni.

izindlela ukuxilongwa

Ungesabi kwesifo kwesikhathi hypogonadism ezingabantu. Ukuthi lesi simo kusho ukutshela udokotela ngesikhathi kokubonisana kuqala. Ngemva ukubonakala izimpawu isifo ngokushesha kumele uxhumane uchwepheshe ofanelekayo. Naphezu sasivumela elikhanyayo isithombe yomtholampilo, isiqinisekiso lesi sifo kudingeka alandele kokuhlaziywa emtholampilo. Kuhlanganisa imisebenzi elandelayo:

• behlolwa;
• ultrasound okhalo;
• karyotype;
• urinalysis;
• isidoda;
• Ukuhlolwa kwegazi-hormone.

Ucwaningo sabelwe nesineke ngayinye. Ngakho-ke, uhlu izenzakalo emitholampilo kungahluka kancane. udokotela kuqinisekisa noma uyakuphika uphethwe kwangaphambilini ngesisekelo imiphumela eyatholakala, esabela yokwelapha.

Izici yokwelashwa

Ukukhethwa indlela ethile yokwelashwa isesikhathini udokotela futhi uzimisele ikhumbula izimbangela zesifo. ekwelapheni hypogonadism ezingabantu ngokuvamile has imigomo eziningana: ukulwa nezifo ezinkulu, nokuvinjelwa ukungazali, nokuvinjelwa nesenzakalo izimila kule izicubu wamasende.

amafomu azalwa naso futhi prepubertal zokugula zivame ukuhambisana nenzalo. Ukuphungula le nkinga akunakwenzeka. Uma endocrinocytes agcinwe testes, kutuswa ukwelashwa ingqondo. Izingane ebekiwe izidakamizwa hormone, kanye nabantu abadala - kumele androgens. In the ukungabikho hormone endocrine zidinga ukuphuziswa kukho konke ukuphila.

Ngesimo yesibili inqubo sokugembula gonadotropic ebekiwe izidakamizwa ngezilinganiso encane. Uma kudingekile, basuke kuhlangene testosterone. A indima ekwelapheni isifo kungokwalabo Gymnastics futhi wamukele Vitamin izakhiwo.

Yonke imithi kuyabekwa ngamunye kuncike isimo sezempilo kanye nobudala isiguli. ukusetshenziswa ukwelashwa esikhundleni nabenzeli hormone is hhayi Kunconywa kwezinye izimo. Ngokwesibonelo, e umdlavuza izilonda wendlala. Okungalapheki isifo samaphaphu, ukubhema, kahle amafutha umzimba zokuphelelwa umoya ukuhlaselwa - kukhona Izimo isihlobo. Kulezi zimo, isinqumo ukuvuma kwe-testosterone izidakamizwa kuthathwe ngamunye.

kokungenela kuhlinzwa

Uma hypogonadism ezingabantu kubangelwa kokukhubazeka emzimbeni ukukhula kwezitho zobulili, okubonisa ukusebenza. Namuhla, ezihlukahlukene ongakhetha ukungenela ukuze kuqedwe lesi sifo. Isibonelo, nge hypoplasia wenduku isetshenziswa phalloplasty, esimweni testis undescended wenziwa yizembe. yenzeka zokwenziwa testis kwenziwe ukuqeda isici yezimonyo. Noma yimaphi kula imisebenzi wenziwa ngokusebenzisa amasu microsurgical.

Isibikezelo ukutakula

hypogonadism Primary, ikakhulukazi azalwa naso, kungenziwa kancane ukulungiswa. Kumayelana uzowubuyisela amakhono yokwakheka futhi functional wenduku. Nokho, ezokwelapha zesimanje kulesetayelekile ejaculation ongakwazi ukuzenza. Inketho kuphela ukuze uthole kabusha ukukhiqizwa kabusha - IVF isidoda ngokusebenzisa ucingo. Ngakho spermatogenesis vnutriyaichkovy kufanele kugcinwe.

Enye umhlahlo ulindele iziguli ukuthi nginesifo hypogonadism yesibili. In amadoda, ukwelapha lesi sifo ezimweni eziningi ukunikeza imiphumela emihle. Ngakho-ke, odokotela abakwazi ukubuyisela umsebenzi zokuzala.

izinyathelo

zokuvimbela Specific yalesi sifo engakaze athuthukile. Phakathi izincomo jikelele odokotela ukubiza lokhu okulandelayo:

• ukwelashwa ngokushesha kwanoma iyiphi isifo;
• umsoco ofanele, ukungabi imikhuba emibi, umsebenzi;
• ezidlulayo wokuhlola ngesikhathi "owesilisa 'odokotela njengoba isilinganiso izifo kanye ngonyaka.

Lezi amathiphu, ngeshwa, akwenzeki ngaso sonke isikhathi ukuvimbela hypogonadism ezingabantu. Ngesikhathi kuqala zako ngokushesha kufanele bafune usizo onguchwepheshe. I ngaphambili udokotela ekwelapheni ezibekiwe, ngokushesha ngeke kusheshe kuphole.