"Gliclazide": analogue, izinkomba, yokusetshenziswa

Omunye pathologies ezivame kakhulu endocrine uhlamvu sikashukela. Iningi leziguli nale Ihlahlubo uhlushwa uhlobo lesi sifo yesibili. Nokugula zidinga ukwelashwa okuqhubekayo kanye nemithi. Zishukumisa ukukhiqizwa insulin emzimbeni uyakwazi ukulungiselela "Gliclazide". izindlela Analogs ungase ube indlela efanayo isinyathelo zokwelapha noma okuqanjiwe ezifanayo. Khetha esikhundleni we imithi yokuqala kufanele udokotela ukuba khona.

Incazelo "Gliclazide" izidakamizwa

I nomuthi "Glikliazid" libhekisela amagama ahlobene of sulfonylureas (second generation) kanye kunomphumela evelele hypoglycemic. Umuthi ingasetshenziswa ekwelapheni isifo sikashukela insulini nasekuthengeni. Umgomo oyinhloko yokwelapha "Glikliazidom" ukunciphisa ezingeni glucose egazini. Futhi ama-carbohydrate evamile futhi lipid umzimba. Ekhemisi ukuthenga imithi kungenziwa ngokuthi "Gliclazide-Agos", "Glidiab-MB".

Isithako asebenzayo of the gama elifanayo kunomphumela omuhle isimo imithambo yegazi, ekubuyiseleni permeability yabo futhi ekuvimbeleni ukukhumuzeka isifo sokuqina kwemithambo yegazi. ukusetshenziswa eside we nomuthi nge nephropathy sikashukela ihlinzeka ukunciphisa okuphawulekayo proteinuria (iphrotheni umchamo). I-ejenti ukwelashwa kwehlisa ingozi mural thrombosis.

Ubuningi esiphezulu isakhi esiyinhloko esebenzayo egazini kulotshwe ngemuva kwamahora 6-12 emva ukungenisa izibhebhe "Gliclazide". Analogue zomuthi is selisungule kahle, kodwa kumele sithathe udokotela ngamunye. Njengengxenye izidakamizwa yasekuqaleni isithako esebenzayo gliclazide Ushintshe ukukhululwa.

Izinkomba ukusetshenziswa

Ngokusho isichasiselo "Gliclazide" inikezwe abantu abanomlando sikashukela (sikashukela), uhlobo 2. Pathology yohlobo yokuqala ihlukile esimweni sesibili iyeke production ozimele ngokuphelele we-insulin. Imbangela eyinhloko isifo ubhekwa ukuguga kwezenzakalo. Nokho, ukuba khona Kilos esengeziwe kanye ukusetshenziswa ngokweqile carbohydrate kungase kuvuse ukuthuthukiswa sikashukela.

Tablets "Gliclazide" manual uncoma ukusebenzisa indlela yokwelapha eyinkimbinkimbi iziyaluyalu microcirculation. Njengoba isilinganiso izifo umuthi wabonisa nokuvimbela nemiphumela enqala sikashukela: unhlangothi, isifo senhliziyo, isifo sezinso, retinopathy.

Izimo

Akuvunyelwe ukuthatha "Gliclazide" (analogue zomuthi kanye) ebukhoneni ukuxilongwa ezilandelayo:

• wamathumbu isimiso;
• leukopenia;
• kwezinso esiteji ezinzima, ukwehluleka hepatic;
• isifo sikashukela (uhlobo 1);
• izifo ezithathelwanayo lapho kukhona ukuphazamiseka kwenqubo ukudla;
• gastroparesis;
• lactation;
• kweminyaka eyi-18;
• ketoacidosis;
• izimo zokucabanga okubangelwa isifo ezidinga ukusetshenziswa insulini;
• sokukhulelwa.

Indlela "Gliclazide"?

Umthamo ejenti hypoglycemic akhethiwe Uchwepheshe ngamunye. I umthamo wansuku zonke ingahluka ngaphakathi 30-120 mg isithako esebenzayo kuye ngobucayi ngezimo zesiguli futhi yobudala bakhe. + Thatha amaphilisi kanye ngosuku ngaphambi kokudla (mhlawumbe esiswini esingenalutho).

Isikali letiphakanyisiwe ayikhuphuki ngenkathi ukweqa eyamukelayo nomuthi. Kwezinye izimo umthamo esiphezulu bengase bazikhandlele mg 320.

Izici zomuthi "Gliclazide"

Analogs ejenti hypoglycemic njengoba belungiselela yokuqala ngokwalo, kuphela sisetshenziswa ndawonye ukudla okunama-kilojoule amancane, okubandakanya ukusetshenziswa isilinganiso esiphansi carbohydrate. Kubalulekile ukulawula ezingeni glucose in the serum igazi ngaphambi nangemva kokudla. Umthamo Lungile zomuthi ngemva engokomzwelo noma engokomzimba ukucindezeleka overvoltage.

Izidakamizwa lingahoxisa ngesikhathi imfiva okudalwa ukusha ebanzi, ukuhlinzwa. Ngezinye reception ngesikhathi esisodwa "Gliclazide" nemithi Ethanol-equkethe, ama-NSAID kukhona ingozi hypoglycaemia. Ethanol kungabangela ubuhlungu besisu, ukuhlanza okungapheli, isicanucanu.

analogs

sulfonylureas zemithi njengokunesidingo ekwelapheni isifo sikashukela. I ebalulekile nebubi babo ahlanganisa ukuthuthukiswa ukumelana naye. Namuhla kunesimo esithi asifane is ebonwe 5% weziguli ezine kamuva sidluliselwe insulini.

Izidakamizwa "Gliclazide", ogama intengo zokhahlamba kusuka ruble 130-160 iphakethe ngasinye (amaphilisi 30), ungakwazi ukushintsha izidakamizwa yenziwe ngohlobo olufanayo. Kususelwa ukukhululwa kwe gliclazide nemithi ukukhululwa ukushintshwa. Ngempumelelo kukhona analogs elandelayo imithi yokuqala:

• "Glidiab".
• "Diabeton MV".
• "Vero Gliclazide."
• "Diatika".
• "Diabetalong".
• "Diabinaks".
• "Glidiab MV".
• "Diabefarm".

esekelwe gliclazide izidakamizwa nethonya elihle ku-microcirculation, Hematology, hemostasis. Lokhu kubaluleke kakhulu iziguli sikashukela sohlobo 2. Flavour ukuthaka imithi ngoba ezishukumisayo insulin kufanele ukuya kudokotela. Qaphela ukuthi nomphumela oqabulayo kubangela ukwenyuka isisindo emzimbeni.

"Diabefarm": yokusetshenziswa

ejenti hypoglycemic itholakala ifomu tablet. Omunye sibhebhe sinamaphutha 80 mg asebenzayo izidakamizwa core gliclazide. Njengoba izingxenye asizayo wasebenzisa i-lactose, magnesium stearate, povidone. Umkhiqizi - inkampani eyenza imithi Russian - ikhiqiza izidakamizwa "Diabefarm MV" Ukukhululwa ukushintshwa. Kulezi amaphilisi umthamo lomcebo asebenzayo kuyehla kube 30 mg. Ukukhululwa kwenzeka phakathi namahora angu-24.

Umthamo ngamunye akhethiwe. Udokotela uyakucabangela ezingeni glucose in the serum igazi, ubudala lesiguli kanye izimpawu zesifo. kokuqala umthamo wansuku zonke kumele singeqi 80 mg. Kamuva senyuselwa 160-320 mg gliclazide.

"Diabefarm" yokusetshenziswa bayakhuthazwa ukuba baphakamise iziguli omdala ngoba okungekho ngempumelelo yokwelapha yokudla nokuvivinya umzimba. Ithebhulethi Ushintshe-ukukhululwa (MW) kufanele kube isikhathi esingu-1 ngosuku. Udokotela angase ukwandisa umthamo ngemva ukuqapha ukuhlolwa igazi ushukela.

side effects kanye ukweqisa izidakamizwa

Ochwepheshe wazi ukuthi imiphumela emibi ezigulini ethola izidakamizwa athuthukile ngokuyinhloko okungathobeli nokushintsha kokudla nokufakwa kanye nezincomo jikelele ekwelapheni eziyinkimbinkimbi. Kahle kungakhuphula izinga likashukela - omunye njalo kakhulu side effects - kuhambisana izimpawu ezifana isifiso yanda, arrhythmia, palpitations inhliziyo, ukukhathala, ukozela.

On the ingxenye ipheshana wokugaya ukudla kungabangela ukwephulwa lokhu okulandelayo:

• ukuqunjelwa;
• ukuhlanza;
• isicanucanu;
• ukusha kwesibindi kohlobo;
• isifo sohudo,
• jaundice holistaticheskaya.

Ezimweni ezingavamile sibonakalise komzimba ezifana ukulunywa, isifuba isikhumba ububomvu. Ezinye izimpawu ze-imiphumela emibi izidakamizwa zidinga yokukhansela yayo.

Overdosing ngokuvamile kuholela ukuthuthukiswa kahle kungakhuphula izinga likashukela, ikhoma hypoglycemic, ukuphazamiseka ukwazi. Phinda lokuhlushwa glucose kungenzeka esebenzisa ekuphathweni emthanjeni solution dextrose (uma isiguli aquleke). Esimweni lapho kukhona izimpawu ecacile kahle kungakhuphula izinga likashukela, kodwa isiguli uhlala bayazi, kufanele athathe esincane ushukela.

Izidakamizwa "Glidiab"

Enye i-ejenti gipoglikekmicheskoe kokuba bamake nomphumela oqabulayo - "Glidiab". Yokusetshenziswa uthi iphilisi elilodwa liqukethe 80 mg lomcebo asebenzayo Gliclazide. iphakethe ngasinye siqukethe amaphilisi 60. Izindleko zomuthi - ruble 110-140. "Glidiab MV", intengo ruble 140-170, ngokuvamile iqondiswa iziguli.

isenzo izidakamizwa kusekelwe kusebenze lamaseli amanyikwe okuyinto ukukhiqiza insulini. "Glidiab" uyakwazi alulame isiqongo wokuqala we-insulin uketshezi, okuyinto liwuhlukanise kusukela ezinye izindlela kusukela iqembu elinabantu sulfonylurea nemikhiqizo.

Ngemva 4 amahora ngemuva kokuthola gliclazide nomuthi waphawula lokuhlushwa esiphezulu e serum. Izidakamizwa ugxile pheshana emathunjini cishe ngokuphelele.

Ukuxhumana nezinye izidakamizwa

"Glidiab" Iziyalezo yokusetshenziswa incoma kuthathwe ngokuqapha therapy okuhambisanayo ne glucocorticoids, i-calcium abamelene, barbiturates, lithium nosawoti. Lokhu kuzokwehlisa kusebenta oqabulayo ejenti hypoglycemic.

Ukwandisa isithako esebenzayo kuzokwenzeka esimweni inhlanganisela 'Glidiaba "nezidakamizwa temlomo antifungal, fibrates, anticoagulants ngokungaqondile, nezinye izinto ezithwala hypoglycemic, Ama-anabolic steroid. Ngaphambi ukwelashwa udokotela kufanele wazise nesineke mayelana izici nokushintsha kokudla nokufakwa.

"Diabeton MV"

Kusho "Diabeton" Ukukhululwa Ushintshe we ketshezi esebenzayo kungokwalabo iqembu sulfonylureas isizukulwane 2nd. I lolwehlukanisa kuba phambi N-equkethe indandatho heterocyclic, esesikhundleni ibhondi endocyclic. Ochwepheshe wazi ukuthi uma uthatha imithi ye-iminyaka engu-2 akazange zikwazi ukumelana naso.

Ithuluzi yenzelwe kuphela ekwelapheni iziguli omdala, kanye izidakamizwa yasekuqaleni "Gliclazide." intengo izidakamizwa French - 320-370 ruble iphakethe ngasinye (30 izingcezu).

Gliclazide lokuhlushwa esiphezulu egazini siyenzeka amahora 6-12 emva ukungenisa tablet. Lokhu kunciphisa inani izidakamizwa engayitholi ngosuku. Ngokuvamile, odokotela batusa usuku ukuthatha 1-2 amaphilisi. Ochwepheshe kanye neziguli abasele okubuyayo kakhulu mayelana nokwelashwa nale izidakamizwa.

Iziguli kufanele uqaphele ukuthi ingxenye izidakamizwa kuhlanganisa ne-lactose. Ngakho hamba nayo ukungabekezelelani isegazini efana noma galactosemia is hhayi Kunconywa.

Ngokwe-nokubuyekezwa, "Diabeton MV" kubhekwa lamathuluzi ngempumelelo kakhulu esigabeni sulfonylurea nemikhiqizo. A inzuzo okuphawulekayo nesenzakalo ezingavamile amathuba okuba nemiphumela engemihle ezigulini ethola izidakamizwa. Kusho ukunquma imithamo kanye nokwelashwa lwemithi can kuphela onguchwepheshe. Isiguli kufanele kuqala ihlolwe. Ngokuzimela ukuthatha imithi aphansi glucose ileveli engathandeki kakhulu.