Co-trimoxazole - izincomo Isicelo

Co-trimoxazole eyisidalwa esinenkululeko elwa namagciwane elitholakala njengoba isixazululo infusions, imijovo, amaphilisi, ukumiswa, ngoba ukungenisa. Izithako main asebenzayo sokulungiselela wathi kukhona sulfamethoxazole futhi trimethoprim, kanye uphiko - ongaphakeme yamangqamuzana isisindo polyvinylpyrrolidone, i-calcium stearate, futhi amazambane isitashi.

izinkomba

Co-trimoxazole isetshenziswa khona kwezifo ezithathelwanayo:

- i-pneumonia, empyema, ukucinana kwemigudu yokuphefumula oyingozi futhi ezingalapheki, iphaphu ithumba, bronchiectasis ;

- epididymitis, prostatitis, urethritis;

- chancroid, isipatsholo, granuloma inguinale, lymphogranuloma venereum;

- typhoid, isifo sohudo esibangelwa amagciwane, imfiva neparatyphoid ebangelwa, shigellosis, cholangitis, Gastroenteritis, ikholera, kuphela njengengxenye ukwelashwa;

- izilonda, induna, pyoderma, imihuzuko, elithambile izicubu abscesses, Erysipelas;

- sinusitis, otitis abezindaba, laryngitis;

- ubuchopho ithumba, septicemia, osteomyelitis oyingozi futhi ezingalapheki, meningitis, brucellosis acute, umalaleveva, toxoplasmosis, blastomycosis South America, ekwelapheni ukukhwehlela whooping esiyingxenye nje yawo yokwelashwa eziyinkimbinkimbi.

Co-trimoxazole - yokusetshenziswa

Lo muthi kufanele kuthathwe kabili ngosuku ngezikhawu amahora 12. Ezinganeni ezineminyaka engu-3 kuya ku-5, umthamo ongashadile 240 mg, oneminyaka engu-6-12 - 480mg, futhi ngemva kuka-12 - 960mg.

Ngokuvamile, ukwelapha izifo sibi akuyona esingaphansi kwezinsuku 5, kodwa emva ukunyamalala izimpawu ebonakalayo lesi sifo kubalulekile ukuthatha amaphilisi izinsuku ezimbili ngaphezulu. Ukwelashwa kwezifo ezifana lymphoma inguinal, ukucinana kwemigudu yokuphefumula okungamahlalakhona, abezindaba acute otitis, chancroid kungathatha amasonto amabili futhi kuze kuphele inyanga ka brucellosis oyingozi futhi typhoid noma neparatyphoid ebangelwa izinyanga 3.

Ekwelapheni isipatsholo ayinzima usebenzisa izidakamizwa "Co-trimoxazole" imfundo olukhombisa ukuthi umthamo kufanele bube 480 mg kabili ngelanga, kodwa kungathatha 2400 mg njalo ngemva kwamahora 8 kuyadingeka ukuze aphinde enze okulinganayo, kodwa kungenzeka olulodwa isicelo zomuthi e isamba 3840 mg.

Ukuze nokwelashwa kwezifo gonococcal Co-trimoxazole esithathwayo kathathu ngosuku kuya kuma-960 mg ngeviki.

Ekwelapheni umalaleveva uqhutshwa izinsuku 2, umuthi esithathwayo kabili ngosuku 1920 mg.

isicinganani

Lapho ethola izindlela "Co-trimoxazole" zingavela imihlola engathandeki ezifana pancreatitis, dyspepsia, sokuzincisha ukudla, enterocolitis pseudomembranous, isicanucanu, stomatitis. Iphinde kungenzeka anaemia aplastic, methemoglobinemia, agranulocytosis, eosinophilia, hypoprothrombinemia, crystalluria, nephritis interstitial kanye nokwehluleka kwezinso.

Ukwamukelwa izidakamizwa kungabangela meningitis aseptic, ikhanda elibuhlungu, arthralgia, hyperkalemia, amawala, ukulunywa, imfiva.

Uma kunemiphumela emibi, kufanele ayeke ukuthatha izidakamizwa. Uma kukhona isidingo ukusetshenziswa yayo yesikhathi eside, kubalulekile ukulawula indlela yokwakheka igazi neuropathy, nezinso isibindi. Ukuvimbela okuvela crystalluria, mhlawumbe emini ukuphuza okungenani 3 amalitha uketshezi.

Izimo

It is nhlobo ukusebenzisa nomuthi ebukhoneni agranulocytosis, ukuntula glucose-6-phosphate dehydrogenase, hypersensitivity kuya izingxenye zalo, B12-ukuntula kwegazi, isibindi noma izinso ukwehluleka, hyperbilirubinemia ezinganeni, leukopenia, ngomlomo izingane ezingaphansi kweminyaka engu 2 izinyanga futhi parenterally ukuba izingane ezingaphansi kweminyaka engu-6.

Overdose "Co-trimoxazole"

Endabeni ka ukweqisa izidakamizwa, kusho izindlela singenzeka crystalluria, ikhanda, ukudla, ubuthakathaka, ukucanuzela kwenhliziyo, ubuhlungu besisu, hematuria, futhi ukozela. Ezimweni ezinjalo kubalulekile ukuba afeze lavage esiswini, uketshezi is injected ukuze ulungise ukuphazamiseka electrolyte, hemodialysis kungenzeka.