AST anda igazi: Izimbangela Nezingozi Ukwelashwa

Namuhla, ngamunye kithi angathola ukuya lab futhi banikela ngegazi, ukuze ubone ukuthi ikhona yini ngeziphambeko sína impilo, futhi uma ikhona, isikhathi kuthathe ekwelapheni. Uma ngemva kokuthola imiphumela yokuhlaziya wembula ukuthi wonke la manani ucishe evamile, kodwa aphakeme amazinga AST, umbuto bese uyavuka: indlela kuyingozi, zimelelani izincwadi ezintathu dolobha ongaqondakali futhi eziningi nezinye izindaba mahhala. Isihloko sethu kuzokusiza uthole izimpendulo kubo.

Kuyini AST

Aspartate aminotransferase, noma AST elifushane - yigama enzyme, oyingxenye ngokuphelele zonke izakhiwo amaselula zomzimba. Kodwa abaningi kakhulu aminotransferase aspartate ungaphakathi myocardium futhi imisipha lwamathambo ke kumaseli sesibindi esingelapheki kubantu abangamaphesenti nezicubu ehlise nezinso. Uma umzimba kuyinto evamile, kanye nezinkomba womsebenzi AST egazini liphansi.

Kodwa ukulimala kwezitho ahlukahlukene noma izinhlelo ze-enzyme uqala akhululwe lingene egazini. Ngakho, lapho ukuhlaziywa kwamakhemikhali, kuba sobala ukuthi AST esiphakeme igazi - ke Kusinikeza isizathu sokusola udokotela ekuqaleni izinqubo elimazayo kumaseli. Enzyme aspartate aminotransferase kuyadingeka ukuze operation kahle amaseli. It wenza ezokuthutha imisebenzi, enifeza ukulethwa amaqembu ngama-athomu kuya acid ehlukahlukene acid.

izinkomba Jwayelekile AST

Jwayelekile amazinga e indlela optical yokunquma (IU) zimi kanje:

• kwabesifazane - kuze kufinyelele 35 IU;
• ngoba amadoda - kuze kufinyelele 41 IU;
• ezinganeni - kufika ku-50 ME.

Ukusabela Reitman-Frankel (mkomol / h / ml):

• kwabesifazane - kuze kube 0.35;
• amadoda - ukuze 0.45;
• ezinganeni - kuze kufinyelele 0.5.

Uma igazi biochemistry yabonisa AST, ingeqi amagugu ecacisiwe - lokhu kubonisa ukuthi uhlelo enzyme kwenhliziyo, isibindi kanye nezinso kuthiwa usebenza kahle, kanye nokusungulwa yeselula zemizimba alilinyaziwe. Nge ngeziphambeko ezikhona kule ukuhlaziywa kanye sokuthi aphakeme AST egazini kumele ihlolwe kanye nezinye nakomaka ethize (troponins, creatine phosphokinase, ALT t. D.).

Mangisho ukuthi laboratories ezahlukene zingasebenzisa reagents ezahlukene kanye nezindlela esifundweni. Ngakho-ke, imiphumela etholakala ezindaweni ezahlukene kungenzeka sithi ukuhluka omunye komunye.

AST anda igazi: Izimbangela

Uma izinga le-enzyme igazi liphakeme, kungase kukhombise khona yisiphi isifo ohlwini olulandelayo:

• isilethikusebenza - ingenye ezivame kakhulu UMTHETHO eliphezulu kakhulu, futhi olubanzi esivimba amanzi umonakalo endaweni, ayanda lokuhlushwa enzyme aspartate aminotransferase egazini;
• evulekile noma avaliwe inhliziyo ukulimala;
• rheumatism isifo senhliziyo;
• angina;
• sokuhlasela kwamasosha omzimba noma myocarditis samafayela;
• Bile umdlavuza imbobo;
• nomdlavuza wesibindi;
• metastatic isibindi lesion;
• cholestasis;
• steatosis utshwala;
• steatosis amafutha;
• ukusha kwesibindi kohlobo viral;
• izilonda anobuthi hepatic;
• ukuhluleka kwenhliziyo;
• ukubhujiswa olubanzi kwemisipha izicubu (wayichoboza syndrome, myositis generalized, myodystrophy);
• pancreatitis oyingozi.

Futhi uma aphakeme AST egazini, ke kungabonakala nasemkhakheni ukulimala imisipha yohlaka, ngotshwala ukudakwa eqinile, ukusha, ukushisa unhlangothi, embolism e imithambo yegazi kanye ezinesihlungu mushroom ubuthi.

Iya kancane ngokuvuswa UMTHETHO isezingeni umsebenzi eqinile emzimbeni futhi ngesikhathi yokwamukela ezinye ejenti kwemithi (sedatives, imithi elwa namagciwane, nokunye. D.).

Yini ongayifunda ekunqumeni amazinga igazi aminotransferase aspartate

Kuleso simo, uma AST egazini sinyukile kancane (mayelana 5 izikhathi), khona-ke kungenzeka lokhu kungenxa FH, yokwamukela ezinye izidakamizwa (barbiturate, statin, imithi elwa namagciwane, izidakamizwa, amakhemikhali okwelapha ejenti, njll).

Lokulingene, ukwanda isilinganiso enzyme (kufika ku ephakeme kunaleyo evamile izikhathi eziyishumi) kungenzeka kubangelwa isifo sesibindi esingelapheki kubantu, isifo sokuqina kwesibindi isilethikusebenza, miokardiostrofiey, icubungula okwenzeka ezilimele izinso amaseli namaphaphu, mononucleosis, umdlavuza.

Uma AST aphakeme kakhulu egazini (izikhathi 10 ngaphezulu) - lokhu utshela udokotela ukuthi nangesineke kungase kube i-hepatitis igciwane esigabeni oyingozi, umonakalo anobuthi kwezakhiwo kwesibindi, ukusha kwesibindi izidakamizwa olubangelwa (acute), futhi lokhu kungase kubonise ukuthi ukugeleza emzimbeni izinqubo ephelezelwa necrosis kwezicubu (isb, izimila).

Ekuqaleni lesi sifo, e isigaba saso acute, lapho inqubo izicubu ekubhujisweni kungenzeka, kukhona eliphakeme aspartate aminotransferase. Ukuncishiswa AST e serum kubonisa ekuqaleni izinqubo zokutakula kumaseli kanye nezinhlaka ekululameni kwesiguli. Iya kancane ngokweqile kwezinkambiso ungeyena uphawu ukwehluleka emisipheni.

Yikuphi kungahlanekezela imiphumela ukuhlaziywa

Ngezinye izikhathi, udokotela, ebona ukuthi AST egazini lenyuke, kodwa bengamtholi isiguli akukho izimpawu ezibonakala lesi sifo, ukhuthaza ukuba unikele ngegazi futhi, futhi lokhu nokuhlaziywa eyengeziwe sikhombisa amazinga evamile enzyme. A bayophenywa enemininingwane kubonakala sengathi isiguli ngosuku olwandulela le blood donation owokuqala wathatha izidakamizwa, okuye kwathinta ngokunemba we izibalo. Ukuze ugweme izimo ezinjalo, kubalulekile ukwazi ukuthi kungahlanekezela imiphumela:

1. Ukuthatha amakhambi athile ezithaka imithi. Kubalulekile ukubeka udokotela ukuthandwa zonke ngokuthatha izidakamizwa. Udokotela angase lokwenqabela ukusetshenziswa kwanoma kunemithi noma amaphilisi owaphuzayo izinsuku ezimbalwa ngaphambi kokunikeza igazi.
2. Ukusetshenziswa imithi engamakhambi: Echinacea noma valerian.
3. Eyanele amazinga okukhishwa esikhulu Vitamin A.
4. Ukukhulelwa.
5. njengemithi yokungezwani komzimba nokuthile Sinzima.
6. Catheterization noma ukuhlinzwa kwenhliziyo yamuva.

Uma AST igazi yanda, kungase kube nezizathu ezahlukene, ngezinye izikhathi ezingalindelekile. Ngakho ungakhathazeki ngokungadingekile ngenxa imiphumela engalungile, it is hhayi Kunconywa amahora ambalwa ukuba unikele ngegazi ukuze zenze ucwaningo oluthile ngemva ukudlula le nqubo elandelayo:

• x-reyi,
• luhlolo rectal;
• ultrasound;
• Physiotherapy;
• X ray.

Kangakanani ucwaningo igazi AST

Ukuhlaziya igazi, anda amazinga enzyme noma cha, kwenziwa ukulandelana elandelayo: ekutholweni igazi aspartate kudingekile ucwaningo kwamakhemikhali. Fence izakhiwo kusuka umthambo kuphela ekuseni kuphela esiswini esingenalutho.

Okokuqala umhlengikazi ingalo eliphezulu ziwumthwalo amahanisi, bese injected vein futhi inaliti idwetshwa mayelana 15-20 ml igazi. I donsa bese zisuswe futhi isetshenziswa kuyo swab umjovo ukotini. Isiguli itsheliwe agobe ingalo endololwaneni nangokuqinile ukunqanda isayithi umjovo ukopha. Ungakwazi uhlale imizuzu embalwa abese hamba ekhaya.

Futhi egazini kuhoxiswe nge Centrifuge ehlukanisa plasma, ekhiqizwa the chemical kunesidingo. ukuphendula kanye AST umsebenzi kunqunywa. Imiphumela ngokuvamile ukulungele ngosuku olulandelayo. Self-decrypting ekhishwe ebulawa imiphumela akukuhle ukwenza, kufanele benze udokotela.

aspartate Ukwandiswa aminotransferase: okudingayo ukwelashwa?

Kubalulekile ukuqonda ukuthi uma ukuhlaziywa kwenziwa futhi waqinisekisa ukuthi kakhulu aphakeme AST egazini, akunakwenzeka ukuthi kwamane kwazenzakalela. Lokhu kungenxa yokuba khona iyiphi zokugula emzimbeni, lapho kubhujiswa isakhiwo isibindi, imisipha yenhliziyo, noma kwezinye izicubu. Lokhu kusho ukuthi AST aphansi ngaphandle ekwelapheni izifo zibangelwa emakamu gxuma enzyme, akunakwenzeka.

Ngakho-ke, lo msebenzi eyinhloko udokotela ukuthola, esimweni lapho AST igazi landa, izizathu zalokho. Lokho iyahola kokuqhuba ekuhlonzweni, bese isabelo ukwelashwa. Ngemva ukuqedwa liyancipha isifo kanye nezinga aminotransferase aspartate.

Indlela sokulungiselela ukuhlaziya kokuqukethwe AST

Ukuze uhlole imiphumela esinembile, kubalulekile ukuba unikele ngegazi esiswini esingenalutho. Futhi kumelwe kudlule lapho isidlo sokugcina okungenani amahora angu-8. Kubalulekile kakhulu ngosuku ngaphambi kokuya lab ukuze uyeke utshwala, ka okunamafutha kanye ethosiwe, futhi ugweme kokubili sindisa ngokomzimba nangokomzwelo noma engqondweni. Ekuseni ngaphambi ukuhlaziywa kungenziwa kuphela baphuze amanzi oluhlanzekile, kodwa akunakusetshenziswa ungaphuzi ikhofi, ayo kanye zezinkambi - ke kungaba nomthelela yokuhlola igazi.

AST anda noma cha, thola hhayi ngaphambi kwezinsuku eziyisikhombisa ngemuva yokudluliselwa kuhlatiya, ukuze babe nesikhathi sokulungiselela. Ngoba kufike umuntu mumbe, mhlawumbe amasonto amabili ngaphambi ochwepheshe cwaningo sinconywa ukuze senqabele imithi. Kuleso simo, uma akhiphe le mfuneko akunakwenzeka, kuba isiqiniseko ukuthi kudingeka azise udokotela wakho ngakho decrypting ukuhlaziywa idatha ukwenze izichibiyelo ezidingekayo noma inqubo esimisiwe ngosuku olulandelayo. Uma kukhona yokungezwani komzimba noma ukukhulelwa, futhi kuyadingeka ukuze wazise udokotela ngakho.

Izinkomba for ukuhlaziya injongo

Uhlaziyo ngenhla kuboniswa izifo ezithile:

• Acute noma isifo senhliziyo.
• Zonke izifo kwesibindi.
• Izifo sokuhamba kwegazi.
• Ukutheleleka.
• esingamahlalakhona kwezinso.
• izifo sokuhlasela kwamasosha omzimba.
• Encephalopathy omsakazo akucacile.
• Ukuphulwa bilirubin umzimba, futhi izinhlobo ezahlukene jaundice.
• Pathology purulent-ukonakala.
• pancreatitis Okungalapheki.
• Cholelithiasis futhi kuphula umthetho we outflow ka Bile.
• izimila ebulalayo.
• izifo ze-endocrine.
• izifo zesikhumba okubangelwa komzimba.
• Lungiselela a ukuhlinzwa okukhulu.
• Ukulimala kuya thorax noma esiswini.

Ngaphezu kwalokho, kunikezelwe ukuhlola Dynamics ekwelapheni pathologies zenhliziyo hepatic futhi imithi elwa namagciwane uma (nokunwetshiwe), ezinobuthi ezihlukahlukene, kanye nokwelashwa ngamakhemikhali.

Mayelana inkomba ALT

Kuyini i-high blood AST, izimbangela zalesi simo, sithole aphume. Manje ake sixoxe izinkomba ezingabalulekile ekuphileni. Ngokuvamile, nabelane kwamakhemikhali kwegazi, udokotela efuna ukubona nje kuphela ezingeni AST, kodwa futhi okuqukethwe kwenye enzyme - ALT.

Lokhu alanine, okuyinto, efana AST ekhona emangqamuzaneni zonke izinhlaka, kodwa iningi lemali yayo uku isibindi kanye nezinso. Lapho kuphakama izinkinga isibindi, ALT emgudwini wegazi. ukwanda kwalo ukuxilonga isibindi ezifweni ezimbi phambi ukubukeka jaundice - uphawu isici kwesibindi ahlukahlukene. Ngakho-ke, igazi okusezingeni eliphezulu ALT yezokwelapha esichazwa ngokuthi inkomba umonakalo uhlaka isihloko.

Uma umuntu isidlulile ekuhlaziyeni kwamakhemikhali kwegazi ALT AST yanda, kungasho ukuthi umzimba kungokoqobo izinqubo sina elimazayo. Khumbula ukuthi kokubili enzyme adedelwa igazi eziningi eziphakeme kuphela uma kukhona ukuphazamiseka izakhiwo amaselula. Lokhu akusho ibonisa isifo. Bafinyelele eziphethweni ezinembile ungenza udokotela, ngemva okwengeziwe izindlela zokuxilonga. Awudingi sokuba netwetwe, kodwa uyephuza akuyona kuwufanele ukuvakashelwa kudokotela.

inkulumo lokuvala

ALT Ukwandiswa futhi AST egazini akuyona umusho, ngisho noma lezi zibalo kude kuyinsakavukela. Into esemqoka - kuba ukuxilongwa ngesikhathi esifanele kanye nokwelashwa beqondiswa uchwepheshe abanolwazi. Sifisa wonke umuntu ukuhlaziywa ezinhle nokuba nempilo enhle!