Anticonvulsants "Topamax": Yokusetshenziswa

Ukulungiselela "Topamax" imfundo libhekisela eqenjini imithi anticonvulsant, okuyinto isenzo siqondiswe ivimbela receptor sodium, ukususwa zibe nokuqeda emsipheni excitation. Ngesisekelo le imithi luyanda umsebenzi acid γ-aminobutyric futhi carbonic anhydrase okusithiyayo umsebenzi we isoenzymes. Ngaphezu kwalokho, i-ejenti antiepileptic "Topamax" (ukuhamba umsebenzisi isethi, igcizelela) evumela ukushintshashintsha kwezwi yohlobo GABAA yokwamukela ukuzwela. Ngo ukusetshenziswa kwalesi imithi isiguli wawubona eqeda ukuvuvukala, analgesic kanye nomphumela antispasmodic.

Iyatholakala izidakamizwa "Topamax" (umsebenzisi ngalokhu futhi kubonisa) ngesimo gelatin amaphilisi, aqukethe njengoba ingxenye main in inani topiramate angu amabili nanhlanu noma amashumi amahlanu. izithako Asizayo kukhona cellulose acetate, ushukela kanye povidone granules. Ukwakheka igobolondo capsule zihlanganisa izinto ezifana sodium lauryl sulfate, gelatin, monolaureat sorbitan, amanzi, ama-titanium dioxide nangoyinki.

Linqume anticonvulsant "Topamax" imfundo manual weluleka ngokuyinhloko nokwelashwa kweziguli kwathiwa unesifo "isithuthwane" noma "ngegama Lennox-Gastaut syndrome." Ngaphezu kwalokho, udokotela ngenkuthalo linqume lokhu remedy abantu abaphethwe migraines, ukuquleka tonic-clonic, ngokwengxenye noma myoclonic. Ngaphezu kwalokho, kuyinto imithi antiepileptic ubhekana usuke ungekho futhi ukwazi ngesikhathi esifushane ukuqeda kwemisipha izinhlungu zibe.

Thatha amaphilisi "Topamax" imfundo esokuba wenqabela abantu hypersensitivity kuya topiramate noma ukusabela iguliswa noma iyiphi nezinye izithako eziqukethwe kwengoma. Futhi hhayi Kunconywa kuyinto anticonvulsant kwabesifazane nomntwana. Uhlu Izimo zihlanganisa lactation ezinzima futhi isikhathi, futhi engu-iminyaka emibili. Ngokucophelela okukhulu kufanele ukuthatha imithi abantu nefrourolitiazom, esingamahlalakhona hepatic noma kwezinso.

Sigweme ethola izidakamizwa antiepileptic kufanele iziguli ezine hypercalciuria.

Ngokuphathelene kungenzeka ukusabela ezingezinhle cuphuluza ukusetshenziswa kwezidakamizwa "Topamax", lapha endaweni yokuqala, kumele uthi ezifana zabiwa njengemali isiyezi, ukunakekela kahle, paraesthesia, ukucobeka, ukukhathala, ukuhluthuka futhi ukozela. Ngaphezu kwalokho, kungase kungasebenzi khona-ke kwehle esesuthi, ukucobeka, nawokuphazamiseka kokusebenza kwengqondo, gipoesteziya, dysarthria, liqhaqhazela, disorientation, futhi lability ngokomzwelo. Kabi esiswini, kolwelwesi, nomlomo owomile, ukopha izinsini, glossodiniya kanye ukuqunjelwa futhi kungenzeka abantu ukuthatha amaphilisi "Topamax". lezi amaphilisi ibe imbangela imisipha amajaqamba, ukuthuthukiswa myalgia noma arthralgia, imfiva kanye nobunzima ukuphefumula.