Ama-substitutes nama-analogues we- "Bravadin". Ukuqhathaniswa nokubuyekezwa

Namuhla zonke iziguli zeshumi ezisepolyclinic zimi emgqeni we-cardiologist. Abantu abaningi bahlushwa izifo zenhliziyo. Amashalofu e-pharmacy agcwele amabhokisi anambala anamaphilisi ukuze aphathe inhliziyo. Imithi ngayinye ebiza noma engabizi, inezihlobo ezihlukile. "I-Bravadin" imithi yesilinganiso samanani esilinganiso. Cabanga ngakho, nezinhlobonhlobo zezilinganiso zayo.

"Bravadin": ubufakazi

Isidakamizwa sinqunyelwe abantu abane-angina pectoris, lapho isigqi sesine esivamile. "I-Bravadin" isetshenziselwa izimo lapho isiguli singenakho ukubekezelelana noma ukuphikisana nokusetshenziswa kwe-beta-blockers, kanye nokwelashwa okwengeziwe uma lezi zindlela ze-beta-blockers zithathwa ngokujwayelekile.

Iqembu lesibili leziguli - elinokukhubazeka kwenhliziyo okungapheli. "I-Bravadin" ithathwa kuleli cala ukuze kuncishiswe imvamisa kanye nengozi yokucindezeleka nalesi sifo. Iningi lezibhedlela kanye nokufa ezivela esifo senhliziyo nemithambo yegazi kwenzeka ngokuqondile ngenxa yezimo ezinzima.

Ukungahambisani nokusetshenziswa kwe-"Bravadin"

Lesi sidakamizwa, njengemithi yonke, sinokuphikisana. Ukukhipha ingozi yezinkinga ngenxa yokuthatha amaphilisi, kufanelekile ukufunda ngokucophelela uhlu lwezingqinamba ezithi "i-Bravadin" inayo. Iziqondiso zokusetshenziswa zifakiwe ephaketheni ngalinye.

Awukwazi ukusebenzisa i- "Bravadin" uma isiguli sinokuphikisana okukodwa noma ngaphezulu:

1. Ukuzwela nokubekezelelana kwe-ivabradine noma ezinye izingxenye eziqukethwe kulo muthi.
2. Uma ngaphambi kokuba ukwelashwa isiguli sibe nesilinganiso senhliziyo esingaphansi kwama-beats ayisithupha ngomzuzu. Lesi simo sibizwa ngokuthi i-bradycardia.
3. Uma kwakukhona i-infarction eyingozi ye-myocardial.
4. Ukuphazamiseka kwe-cardiogenic.
5. Iziguli ezine-hypotension ezinamandla ezingezansi azinikezwa amaphilisi "Bravadin". Uma isiguli sinemishanguzo ye-systolic (engenhla) ngezansi ezingamashumi ayisishiyagalolunye, futhi ingcindezi ephansi (i-diastolic) engaphansi kwama-50 - lokhu kuyingozi efanayo.
6. Isifo esinzima sesibindi.
7. Ubuthakathaka be-sinus node kanye nokuvinjelwa kwe-sinoatrial.
8. Ukuhluleka kwenhliziyo okungaguquki noma okunzima, angina engaqiniseki.
9. Akuvunyelwe ukwamukelwa ngesikhathi esisodwa "kwe-Bravadin" ngemithi ethile: ama-antibiotics (iqembu lama-macrolide), ama-antifungal (i-azole group), i-nefazodone ne-HIV protease inhibitors.
10. Ukulawulwa kokusebenza kwesigqi, okuvuselelwa ngaso sonke isikhathi.
11. Lapho ukhulelwe futhi uncelisa.
12. Iziguli ezingaphansi kweminyaka eyishumi nesishiyagalolunye ayinikezwa "i-Bravadin", ngoba kulolu qembu lobudala, ukusebenza komuthi nokuphepha kwawo akuzange kufundwe.
13. Ukwehluleka emzimbeni we-lactase nokubekezelelana kwe-lactose.

Ngezifo nezimo ezibekwe ngenhla, awukwazi ukuthatha izidakamizwa. Kunezimo ezithile zomuthi wokucophelela kwezifo ezilandelayo:

• Ukuguqulwa kwama-retinal;
• Uma kungengakapheli isikhathi eside, uhlangothi lwadluliswa;
• Ukukhubazeka okulinganiselwe kwe-hepatic;
• Ukungasebenzi kahle kwe-ventricular (okungaqondakali);
• Isikhathi eside eside QT (ukuzala) noma ukusetshenziswa kwezidakamizwa ezandisa lesi sikhathi.

Uma usebenzisa izidakamizwa ezithile, "i-Bravadin" kufanele ithathwe ngokuqapha okukhulu futhi ngaphansi kokuqondiswa kochwepheshe. Udokotela ozofika kufanele azi ukuthi kukhona omunye wabo owenzayo, futhi anqume ukuthi kuyadingeka yini ukubeka "i-Bravadin". Imiyalo yokusetshenziswa kwalesi sidakamizwa kufanele iphinde ihlolwe ngokucophelela yisiguli ngokwayo. Uma usebenzisa noma yiziphi izidakamizwa udokotela azi, ngakho kungcono ukuthi azitshele ngakho. Kulesi simo, uchwepheshe uzocubungula ama-analogs. "I-Bravadin" angeke ibekwe uma ebheka ukuthi isicelo sakhe singaphephile.

Isilinganiso nomzila wokuphatha

Lesi sidakamizwa ngokuvamile sidliwa ekuseni futhi kusihlwa ngokudla.

Lapho ukwelashwa nge-angina, isilinganiso sokuqala singama-milligram ayishumi ngosuku, lokhu "i-Bravadin" 5 mg yethebhulethi eyodwa kokubili okulinganiselwe kwamanani. Esikhathini esizayo, emva kwenyanga, udokotela angakwandisa umthamo ube yizigidi eziyizinkulungwane eziyishumi nanhlanu (kabili ngelanga kuthebhulethi ka-7.5 mg).

Umthamo wezidakamizwa wehlisiwe uma, ngesikhathi sokwelashwa, isiguli siqala ukonga, sinciphise ukucindezeleka kwegazi, futhi ukukhathala kwenzeka ngokushesha. Kulolu daba, udokotela ngeke akhiphe lesi sidakamizwa, kodwa anciphise umthamo wayo ezingeni eliphansi - ama-milligram amahlanu ngosuku (kabili ngosuku, isigamu sebhelethi ka-5 mg).

Isidakamizwa kufanele sikhishwe ngaphandle kwesicelo, uma ngemuva kokunciphisa umthamo izimpawu zangaphambili zihlala, futhi ukushaya kwenhliziyo kuhlala ngaphansi kwezingubo ezingamashumi amahlanu ngomzuzu.

Lapho ukwelapha ukuhluleka kwenhliziyo (okungapheliyo), "i-Bravadin" inqunywe emithini efanayo.

Uma isiguli singaphezu kweminyaka engamashumi ayisikhombisa nanhlanu ubudala, imithi ishiwo esilinganisweni esincane kunazo zonke - ama-milligram amabili nohhafu (isigamu sebhelethi) kabili ngosuku. Eminye yokwelashwa okuphumelelayo kanye nokungabikho kwemiphumela emibi, umthamo wanda.

Uma, ngenxa yezizathu ezithile, izinkinga noma imiphumela emibi zenzeka ngesikhathi sokungeniswa, ezinye izidakamizwa noma izifaniso zibekiwe, "i-Bravadin" ikhanseliwe.

Imiphi imiphumela emibi engaba khona kusukela ku- "Bravadin"

Uma uthatha lesi sidakamizwa, imiphumela emibi engafuneki ingabonakala. Uma uqale uzizwa unzima kakhulu, waphawula ezinye zezinkinga ezibalulwe ngezansi, bese uthintana nodokotela ngokushesha. Mhlawumbe uzonikezwa ama-analogs. "I-Bravadin" ingabangela ukubonakala kwezimpawu ezinjalo:

• Umbono ongenakwenzeka (imibukiso engafanele, umqondo wokukhanya ungashintshwa);
• Ukuzwa ukukhubazeka (i-tinnitus ingenzeka, ukuzwa kungase kube kubi kakhulu);
• Ukuphazamiseka emsebenzini wenhliziyo (ingcindezi ingaba ingalawuleki, i-palpitation ingase ibonakale, ukucindezela kuzovama ukunciphisa);
• Ubuhlungu ekhanda, isizungu, ukuphelelwa amandla (lokhu kungaba imbangela ye-bradycardia, kulokhu udinga ukuhamba udokotela ngokuphuthumayo, udokotela uzokwehlisa umthamo noma anikeze omunye umuthi, ukukhansela "i-Bravadin");
• I-kungenzeka ye-dyspnea;
• Esikhumbeni kungase kube nemihlathi, itching, kukhona kungenzeka edema;
• Umswakama, isifo sohudo, noma ukuqotshwa;
• I-spasms nezinhlungu ezimiseleni;
• Ukukhathala okusheshayo, ukulala nokulala.

Ezimweni eziningi, imiphumela emibi ayibonakali. Isiguli ngokwayo singathukuthelisa izimpawu ezingadingeki, uma uzinikezela ngemithi, akulungile ukuthatha "i-Bravadin". Imiyalo yokusetshenziswa (inothi lokuphawula kweziguli) lokhu kulula futhi kuqondakala. Ngesikhathi sokwelashwa kuyadingeka ukuba ufike emamelweni, ugcine yonke imithetho yokwelapha.

"Bravadin": impendulo yesiguli

Sizama ukufunda ngakho kwezinye iziguli ezitholile kakade ngaphambi kokusebenzisa izidakamizwa ezintsha. Ungabi nabangane njalo abaye baqokwa umuthi ofanayo. Indlela elula yokubona izibuyekezo ku-intanethi, lapho abantu abaningi bexhumana khona ne "Bravadin". Ukusetshenziswa kwalesi sidakamizwa iziguli eziningi kubonisa ukuthuthukiswa okusobala empilweni. Abantu abaningi abasebenzisa le mithi babhala ukuthi abazange babe nemiphumela emibi.

I-cardiologists iphawula ukuthi kulula ukusebenzisa (bheka "Bravadin": imiyalelo yokusetshenziswa). Intengo (okufanayo ingaba eshibhile futhi ibiza kakhulu) ifanele iziguli, ngoba "i-Bravadin" imithi yesigaba samanani esilinganiso. Ngamhlanjesi kwezinye izidakamizwa ezihlukahlukeneko zibiza ukusuka kuma-ruble angamakhulu amane kuya kwamakhulu ayisithupha.

Ukuqhathaniswa, njengoba iziguli ziphawula, nazo azikho ngobuningi obufanayo njengoba zingatholakala ezifanisweni ezingabizi. Ngakho-ke, abaningi bakholelwa ukuthi kungcono ukuthenga isidakamizwa esinikezwe udokotela kunokuba ungaboni kubalingani babo okubekwa kuzo.

"I-Ivabradin": ama-analogues "we-Bravadin"

Esinye sezifanekiselo ezivame kakhulu ze "Bravadin" yi- "Ivabradin". Lesi sidakamizwa sinqunyelwe i-angina pectoris, ukuhluleka kwenhliziyo okungapheli. Kungabuye ibekwe ngokutheleleka ngokujwayelekile ngezidakamizwa ezithile ukuze kuvinjelwe futhi kuncishiswe ingozi yezinkinga ezinkulu.

Uyini umehluko phakathi kwe "Ivabradin" ne "Bravadin"

Okuyinhloko yalezi zidakamizwa i-ivabradine hydrochloride. Ku "Bravadin" izinto ezengeziwe ezisizayo zengezwe: i-glycerol, i-magnesium stearate, i-titanium dioxide ne-silicon, i-macrogol, i-hypromellose. Kusukela kulezi zithako izidakamizwa azishintshi, ukuhlushwa kwe-ivabradine kuyafana ne-Ivabradine ngokwayo.

Ukungafani kokusetshenziswa kwezidakamizwa kuyafana. Umehluko kuphela osesiswini esisodwa - ukungahambisani ne-ivabradine noma ezinye izingxenye zomuthi - lokhu kuphela "kwe-Bravadin". Ku "Ivobradin" azikho izingxenye ezengeziwe.

Imiphumela emibi yalezi zidakamizwa nayo iyafana. Faka isicelo futhi lokho kanye nezinye izidakamizwa kabili ngosuku, futhi umthamo wanda noma wehla. Kulaba asebekhulile, umthamo wokuqala awuncane futhi ukwemukelwa "i-Ivabradin", futhi uthatha "i-Bravadin".

Ukubuyekeza: ama-analogues we- "Bravadin" ayabiza kakhulu.

Abantu abaqokwe "i-Ivabradin", babuza ekuxhumaneni nomphakathi, ngingayifaka esikhundleni "nge-Bravadin"? Yiqiniso, lo mbuzo kufanele ubuzwe udokotela, kuphela ongakwazi ukubeka futhi ukukhansela izidakamizwa. Ngokweqiniso, kungenzeka, ngoba isenzo sabo sinjalo, sinikezwe futhi sikhanseliwe ngezimpawu ezifanayo. Khuluma nodokotela wakho mayelana nokuthi kungenzeka yini ukuthi umuthi ungene esikhundleni.

"I-Ivabradin" izindleko ezivela ku-ruble eyodwa kuya kwesigamu nezinkulungwane ezidakamizwa.

"Koraksan" njenge-analog ye "Bravadin"

"Koraksan" kanye ne "Bravadin" ne "Ivabradin", itholakala ngendlela yamathebulethi. Bafika futhi nesilinganiso semililogram emihlanu nesikhombisa nengxenye.

Nika "i-Koraksan" ezifweni ezifanayo - i-angina, inhliziyo engapheli kanye nesifo se-vascular, njengokungeza ku-beta-blockers. Lesi sidakamizwa, njenge "Bravadin" ne "Ivabradine", sinciphisa izinga lenhliziyo.

Kubalulekile ukukhumbula: ayikho imithi ekhonjiwe ngenhla esetshenziselwa ukuphatha i-arrhythmia.

"I-Koraksan" ifana kakhulu nokwakheka ku-"Bravadin", ngoba iqukethe izinto ezengeziwe nokusizayo. Lona umehluko omkhulu phakathi kwezidakamizwa ezivela "i-Ivabradin".

"Bravadin" noma "Koraksan": yini engcono

I-cardiologists ibeka lezi zidakamizwa ngokuyisisekelo. Bangabika bobabili. Ukungafani kwezidakamizwa kuyafana, nemiphumela emibi futhi.

Abantu abaningi banombuzo ngokuthi iyiphi yalezi zidakamizwa ezingcono futhi eziphumelela kakhulu. Abanye baze bazame ukuphikisana, bephikisana ngokuthi ngokuthatha umuthi owodwa, abazange bazizwe ukuthuthukiswa okunjalo okwenziwe umuthi wesibili.

Ngakho yiliphi iqiniso? Uma sibheka ukubunjwa kwale mithi, akucaci ukuthi yiziphi umehluko wabo. Amathebulethi akhiqizwa ezinyangeni ezifanayo, futhi zombili zihlanganiswe ne-membrane yefilimu evikela ukucasuka kwezindonga zesisu.

Isidakamizwa sisetshenzisiwe ezilinganisweni ezifanayo, ezilingana nenani lezikhathi ngosuku (kabili ngesikhathi sokudla). Izinkomba zokusetshenziswa nazo zifanayo, azikho izengezo noma ukuphikisana okuhlukile.

Ngakho yiziphi izidakamizwa ezahlukene? Impendulo yinye kuphela: zenziwe ngamafemu ahlukene, intengo nabo bahluke.

Abaningi bakholelwa ukuthi "i-Koraksan" ingcono, ngoba ibiza ngaphezulu. Ngakho-ke isayensi ye-psychology yomuntu ihlelwe: yini eshibhile, ebi kakhulu emgangathweni. Kungenxa yalesi sizathu odokotela abaningi abangakhetha "i-Koraksan", kodwa uma kungekho ekhemisi, lo mkhemisi uzonikeza "i-Bravadin" noma "i-Ivabradin". Ukuthenga ngesibindi noma esinye isidakamizwa, bahluke kuphela ngentengo.

Esikhathini sokuqokwa okulandelayo, tshela udokotela wakho ukuthi uthenge omunye umuthi. Kunoma ikuphi, ochwepheshe ohola ukwelashwa kwakho kufanele azi kahle ukuthi uthatha ukuthini.

Uma wesaba ukuthenga esinye isidakamizwa, khona-ke thintana nodokotela wakho mayelana nokuthi kungenzeka yini ukuthengwa okunjalo, noma uya kwezinye i-pharmacy. Endaweni ethile kukhona imithi enikezwe yona.

"Bravadin": ukubuyekezwa, ama-analogs

I-Vivaroxan, i-Bravadin, i-Ivabradin ne-Coraxan yizilungiselelo ze-analog. Uma engekho omunye wabo, ungakwazi ukushintsha ngokuphephile omunye. Izakhiwo zezidakamizwa zihloselwe ukuphatha izifo ezifanayo - ukuhluleka kwenhliziyo okungapheli kanye ne-angina pectoris. Lezi zidakamizwa kufanele zibekwe udokotela kuphela, kungabikho icala lokusetshenziswa kwesinqumo esizimele.

Lezi yizidakamizwa ezinzima "zenhliziyo", kufanele ziphathwe ngokuqapha okukhulu. Gcina kuphela ezindaweni ezingeke zifinyeleleke ezinganeni.

Umphumela wale mithi uhlose ukunciphisa isilinganiso senhliziyo. Awukwazi ukuthathwa izinhlungu enhliziyweni.

Ukubuyekeza mayelana nazo zonke lezi zidakamizwa zihle kakhulu. Abantu abaningi abathatha esinye sezifaniso bhala ukuthi abakwazi ukushintshaniswa. Kodwa azilungile. Ungathatha noma yiziphi izidakamizwa, kodwa kufanele uqale uthintane nodokotela wakho.

Abanye abazi ukuthi yini ehlukanisa lezi zidakamizwa, ngisho nokuba khona kwezifaniso. Uma okufanayo "Koraksan" kubonakala kuyabiza kuwe futhi ungenalo ithuba lokuthenga, bese ubuza udokotela ukuthi akhethe i-analog engabizi kakhulu. Ezimweni eziningi, "i-Bravadin" izoqokwa. Kuyabiza kune "Ivabradin", "Koraksan" ne "Vivaroxan". Umehluko emanani lukhulu - kwezinye izimo kuze kube yi-ruble eyizinkulungwane.

Umthelela wezidakamizwa ufana ncamashi, ngakho ungesabi ukushintshela ekhethweni elingabizi.

Abanye babhala ukuthi besaba ukuya "eBravadin", badideka umehluko emanani. Uma wesaba, thatha imithi endala.

Abanye babhala ukuthi uma bethatha i-Coraxan, bazizwa bengcono. Yashintsha ngokushelela ku "Bravadin" futhi kwakukhona nemiphumela emibi. Njalo kunjalo lapho ingqondo idlala nomzimba. Umuntu nje wayengathembeli i-analog eshibhile, kodwa wanquma ukuzama ngenxa yomnotho. Ukuzikhukhumeza njalo lokho okungabizi - kusho okubi, waqala ukulalela ukungavumelani okuncane kakhulu. Lokhu kwaba nomthelela ohlangothini, nakuba imbangela ingabangelwa ukukhathala okujwayelekile noma ukudla ngokweqile.

Noma yini oyibhala kwi-intanethi, ithembele kuphela kumbono wecwaningi, udokotela ophatha wena.