Umuthi 'tizanidine ": yokusetshenziswa, into eyodwa. "Tizanidine-Teva", "tizanidine-Ratiopharm"

Yini imithamo enqunyiwe izidakamizwa "tizanidine?" Yokusetshenziswa kwe-nomuthi uvezwa ngemuva kwalokhu. Futhi, kusuka mathiriyeli lo sihloko uzofunda mayelana ngayiphi indlela ikhiqizwa, kusho kusho ukuthi ingxenye yayo, noma has emibi, kanye contraindications nozakwabo.

Ubujamo, incazelo, ukwakheka

Uyini Ukwakheka has a izidakamizwa "tizanidine?" Iziyalezo yokusetshenziswa uthi ingxenye esebenzayo lokhu umuthi tizanidine. Futhi isakhiwo se-nomuthi kubhekwe yakhiwa njengoba excipients lactose anhydrous, colloidal Silicon dioxide, microcrystalline cellulose futhi stearic acid.

Izidakamizwa "tizanidine," lapho imfundo linamathele ibhokisi, eyenziwe ngendlela amaphilisi round emhlophe. Kolunye uhlangothi strip kuhlukane Isidakamizwa, kanti eyesibili - akubiza T4 kanye T2.

izici kwemithi

Uyini lo mshini wezenzo "tizanidine" izidakamizwa? Yokusetshenziswa ibonisa ukuthi kuba relaxant kwemisipha. Emva kokuthola amaphilisi ngaphakathi izidakamizwa izidakamizwa esebenzayo kunciphisa lwamathambo imisipha tonus, ukwehlisa ukumelana kwabo ezinyakazayo yekwentiwa kanye deceleration ukusabela spasmodic kanye nekusita izinga ezingafanele.

Kulokhu osekushiwo kungaba kuqashelwe kalula ukuthi izidakamizwa kubhekwe ikhuthaza ukusebenza kwemisipha-eziphumulele. Lokhu kwenzeka ngenxa yokucindezelwa polisinapticheskie ikhaliphe umgogodla. Lo mphumela kungenxa ukukhululwa kwama-amino acid kusukela ezikhumulweni (presynaptic) ka interneurons umgogodla.

amapharamitha pharmacokinetic

Yiziphi imingcele pharmacokinetic has izidakamizwa "tizanidine" (amaphilisi)? Yokusetshenziswa kulokhu unika ulwazi olunzulu.

Ngemva kokuphathwa ngomlomo nomuthi is egxile ngokuphelele. bioavailability elingaphezu kukahhafu imayelana 40% (ngenxa pass olubanzi lokuqala ngokusebenzisa isibindi).

I asebenzayo izidakamizwa izidakamizwa abelwa zonke izinhlelo nezicubu. ebudlelwaneni bayo nalowo amaprotheni cishe 30%.

Ingxenye-ukuphila zomuthi kuyinto 2.5 amahora. Cishe ama 95% we umthamo akheka. Kuboniswa nomuthi ngokusebenzisa izinso (cishe 60%) kanye pheshana emathunjini (cishe 20%).

izinkomba

Kwezinye izimo, libeke izidakamizwa "tizanidine?" Ukusetshenziswa kwalesi imithi ethile kuyaphumelela zisesimweni spastic kwemisipha lwamathambo, okuyinto eyenzeka izifo lapho izinzwa ezifana:

• unhlangothi;
• esiwohlozayo nomgogodla;
• myelopathy ezingamahlalakhona;
• yi-multiple sclerosis.

Futhi imithi "tizanidine" siboniswa ubuhlungu bemisipha namalunga, okuyinto ukuthuthukisa ngenxa yokwehlulwa sokukhubazeka komgogodla.

Izimo

The main futhi mhlawumbe contraindication kuphela kwalesi izidakamizwa kwandile ukuzwela isiguli tizanidine. Futhi, asivunyelwe ukuthatha ngokuhlanganyela izindlela ezifana "Ciprofloxacin" futhi "Fluvoxamine".

Izidakamizwa "tizanidine": yokusetshenziswa

Ngokusho imiyalelo, kokuqala Isikali "tizanidine" nomuthi kuyinto 2 mg.

Njengoba umphumela izidakamizwa ifinyelela isiqongo 1-2 amahora buhlanjululwe ngemuva kwamahora 3-6, ukwelapha kufanele sigcwaliswe ngezikhawu amahora 6-8. Ngakho, emini kufanele kube hhayi ningi than amaphilisi 3.

Umthamo nomuthi liyakhula kancane kancane ukuba 4 mg (umthamo ngamunye). Nokho, ngokwenza kanjalo kuphela icala uma, ngemva 4 izinsuku impatho yi engakaze wazwakalisa.

Umthamo Imininingwane nsuku zonke zomuthi akufanele futhi iyophakama kuno-mg 36. Ngokuphathelene Isikali amayunithi, yokwamukela ezingaphezu kuka 16 mg Ochwepheshe engakaze wafunda.

• Ngo esingamahlalakhona kwezinso. Nale uphethwe namaphilisi ngokucophelela okukhulu.
• Ukukhubazeka e kokusebenza kwesibindi. Izidakamizwa "tizanidine" ngokuqapha Kunconywa abantu abanale yiluphi uhlobo yokwehluleka kwesibindi. Kulezi iziguli, umthamo ngamunye kumele kungancipha. Kuyadingeka ukuba njalo hlola lizinga aminotransferase. Ukwelusa sokuqala esenziwa inyanga eyodwa ngemuva Ukuqalwa yokwelashwa.

amacala ukweqisa izidakamizwa

izimpawu zokwelashwa ezenzeka ngokumelene isizinda ukweqisa izidakamizwa angase abe kwemithi ehluke ngokuphelele. Ezimweni eziningi, iziguli ukucobeka, ukudideka, ukozela futhi equlekile. Ngaphezu kwalokho, izidakamizwa ebulilini kungabangela ukungasebenzi kwekhono imisipha yenhliziyo, kuhlanganise izindawo elivela kuzo bradycardia futhi hypotension.

side effects

Zikhona yini imiphumela emibi e seziguli ezithola "tizanidine" izidakamizwa? Yokusetshenziswa (omqondofana ithuluzi kuboniswe ngemuva kwalokhu) ifundeka kanje ukuthi nomuthi kuncike kungabangela nomlomo owomile, ukozela, hypotension, bradycardia, wehlise blood pressure, isiyezi, imisipha amajaqamba, ukukhathala, ubuthakathaka, ukukhathala, ukubona izinto ezingekho okuvezwa ukudungeka kwemizwa, hepatotoxicity, iziyaluyalu kwesibindi.

Kakhulu akuvamile iphathwa nale izidakamizwa ikhuthaza ukubukeka Stevens-Johnson syndrome, dermatitis exfoliative, ukushaqeka anaphylactic, tachycardia ventricular, isifo sokusha kwesibindi, ukucindezeleka, ukuquleka, ukuqaqamba kwamalunga omzimba, amawala, paraesthesia futhi liqhaqhazela.

izidakamizwa ekuhlanganyeleni

Ngaphambi kokusebenzisa "tizanidine" izidakamizwa kufanele ufunde imiyalelo ngokucophelela. Leli gama lembula izici ezilandelayo kwezidakamizwa uhlangana:

• Lihambisana "ciprofloxacin" futhi "Fluvoxamine" Kungenzeka kakhulu wehlise blood pressure, futhi ukuthuthukisa ukozela. Ngaphezu kwalokho, ezifana amalungiselelo eziyinkimbinkimbi kwephula womuntu lengqondo imisebenzi.
• imithi yokwelapha Ngesikhathi CYP1A2 inhibitors (isib, "zileuton" "Fluoroquinolones", "Amiodarone", "Mexiletine", "propafenone" "Verapamil," "Cimetidine" "Famotidine" "acyclovir" futhi "ticlopidine") akuvunyelwe contraindicated.
• Akunconyelwe amaphilisi kuhlanganiswe "tizanidine" nge izinto zokuvimbela inzalo ngomlomo. Uma isimo samanje isiguli sidinga ekuphathweni kanyekanye lezi imithi, komthamo wokuqala kufanele kube omncane. Reception ebulilini zomuthi kungaholela komzimba okufana hypotension, bradycardia futhi hypersomnia.
• Hlanganisa lokhu izidakamizwa ngotshwala is hhayi Kunconywa. Lokhu kungenxa yokuthi utshwala kwandisa lokuhlushwa esebenzayo izidakamizwa izidakamizwa egazini, futhi lokhu kungaholela imiphumela okungafunwa.

eshalofini yokuphila, isitoreji nokudayiswa izimo

Tablets "tizanidine" kwabiwa ngezinkulumo Pharmacy imithi kadokotela. Kufanele mhlawumbe aqukethe ezingeni lokushisa elilingana endaweni emnyama. Ezidingekile ukuze sivikele izidakamizwa kusukela izingane ezincane.

Impilo izimali kuyinto engu-3. Emva kwalesi sikhathi-ke akuvunyelwe ukuthatha.

Inani, bomcondvofana kanye analogue zomuthi

Ezahlukahlukene izidakamizwa ezifana "tizanidine," "tizanidine Ratiopharm" futhi "Teva tizanidine?" Yokusetshenziswa lezi izindlela liqukethe izinkomba esifanayo, imiphumela emibi, Izimo, izindlela zokuphatha kanye imithamo. Umehluko kuphela phakathi kwemithi okukhulunywe ngabo lapha bangabantu abakhiqizi yabo. Ngakho, kuzo zonke lezi zimali kungase kubhekwe njengokuvamile lahlotshaniswa.

Ngokuqondene 'tizanidine "izidakamizwa esiyingqayizivele, ke zihlanganisa izidakamizwa ezifana" Sirdalud "," Tizalud "futhi" Sirdalud MP. "

Kungakanani kukhona "tizanidine," "tizanidine Teva" futhi "tizanidine Ratiopharm"? Regulations yayilokhu izidlela nje lezi izidakamizwa, ingabe phenduli umbuzo othi. Ukuze ukwazi intengo lezi izindlela uzobona kuphela bakwazi ukuphikisana. Njengomthetho, akusiyo eliphezulu kakhulu futhi ruble mayelana 120-170 Russian (kuye ngenani amaphilisi ngamaphakeji nomkhiqizi).

Kufanele ngokushesha kuqashelwe ukuthi nomuthi "tizanidine" has a izindleko akubizi (isibonelo, analogs ezifana "Sirdalud", "Tizalud" futhi "Sirdalud MR" kukhona okuncane ezibizayo, ruble mayelana 240-270). Yingakho iziguli eziningi makudle kwabo izidakamizwa kuqala.

imithi Izibuyekezo

Manje uyazi ukuthi kungani linqume izidakamizwa ezifana "tizanidine," "tizanidine Ratiopharm" futhi "Teva tizanidine." Umsebenzisi ukwamukelwa kwala magciwane seyenziwe ngenhla.

Iziguli abake wasebenzisa leli imithi, bawuthwale ngezindlela ezahlukene. Iningi Izibuyekezo enze kube nokwenzeka ukuba siphethe ngokuthi lesi sidakamizwa "tizanidine" alisho ngaso sonke isikhathi zakwazi ukwenza lokho okulindelwe iziguli.

Abantu abaningi bathi lokhu izidakamizwa kwelinye izimo ezintathu ezibangela imiphumela emibi ezifana amajaqamba ezinzima lapho ukhwehlela nobuhlungu bomzimba. ukusabela okufanayo kwenzeka ngokushesha ngemva kwesicelo se-nomuthi.

Ngemuva kokusebenzisa amaphilisi yesibili, ezinye iziguli sizizwe sibuthakathaka, isiyezi, nokunxanela ukuba ahlanze. Lapho izimpawu ezinjalo, ochwepheshe batusa ukuyeka ukuthola izimali, noma umfutho wabo wande.

Kwezinye izimo, ngemva kokusebenzisa "tizanidine" abantu babe nezinkinga ingcindezi nasesiswini, futhi palpitations inhliziyo.

Kufanele kuqashelwe ukuthi okubuyayo kusukela izidakamizwa kokubuyekezwa alikho ngempela. Phakathi kwabo kukhona ukutholakala kanye nezindleko ongaphakeme zomuthi.

Ngo Ngokwalokho osekushiwo ngenhla kumele lwaphetha ngokuthi ukuthatha imithi "tizanidine" futhi omqondofana yayo, kuphela ukuba kuboniswe futhi kuphela kadokotela.

Banikezwe inqwaba ukusabela ezingezinhle, ochwepheshe is hhayi Kunconywa ukusebenzisa izidakamizwa ngesikhathi sokukhulelwa futhi ngesikhathi ibele, kungenjalo kungase kube nomthelela ongemuhle impilo umntwana noma ingane.