IHC cwaningo - Iyini?

Umdlavuza kukhona ngokoqobo esibi kakhulu iningi labantu. Kodwa ukuze ngesikhathi esifanele ukubona inkinga engathí sina futhi uqale ayibulale ngempumelelo, survey ekhethekile kufanele kwenziwe. исследование. Omunye wabo - cwaningo IGH-.

Zofuzo, receptor nokukhula izici

Izizathu ngqo ezibangela amaseli ngenkuthalo bahlukanise, ukwakha neziqu ezintsha, ngokuvamile Oncology focus, isayensi ayikaziwa. Kodwa nakhu ukuthi ukukhula amangqamuzana, isivele eyaziwa kahle. Izicubu amaseli abe eyinkimbinkimbi. -рецепторы. Uma uyikha phezulu le cell kukhona okuthiwa YENA R-2 ama-receptor. Bakhonza njengabashumayeli uhlobo antenna, ulalele umyalo zomzimba. берет начало от английского словосочетания human epidermal growth factor receptor 2 , что в дословном переводе значит "рецептор человеческого эпидермального фактора роста". Phela, isifinyezo YENA R-2 uvela kusuka ibinzana English womuntu epidermal ukukhula factor yokwamukela 2, ngokwezwi nezwi elisho ukuthi "yokwamukela ngumuntu epidermal ukukhula factor." Kuyinto lezi ezenza futhi abangele esitokisini ukuhlukanisa, zikhule futhi okuzivuselela.

Active umsebenzi yokwamukela futhi isimila

Ngeshwa, umzimba womuntu akusebenzi njalo njengoba kufanele kube, kungakuhle kakhulu, ngaphandle ukwehluleka nezifo. -рецепторы начинают активно получать команды "делиться и размножаться". Inqobo nje isayensi akazi kahle ukuthi kungani, kodwa kuyenzeka ukuthi YENA R-2 ama-receptor sebeqala ukuthola imiyalo "uhlukanise futhi uphindaphinde." Futhi njengoba lezi zinto yeselula esiphezulu kakhulu, benza amaseli ukukhuthalele sokuhlukanisa, ukwakha isimila. Luhlolo kuphela izinkinga zempilo, ezihlanganisa IHC -Studies usivumele ukuthi linqume isimo izimila, kanye isibikezelo ukwelashwa kanye ukuphila kwesiguli.

Isimo isakhi sofuzo yesimila

Umdlavuza imfundo wezokwelapha wesimanje zinqunywa isimo umphumela ukwelashwa kwama-hormone. Lokhu isimo kungenzeka negative (negative) noma omuhle (positive). Cacisa uhlobo izimila kusiza IGH- cwaningo. Lokho kukhombisa immunohistochemistry? Lolu cwaningo kusiza ukusungula neoplasms hormone engaphansi - isimo gertsept futhi, ngakho-ke, ukukhetha okulungile indlela yokwelapha ukuze uthole imiphumela ngempumelelo.

Negative futhi omuhle

Yini gertsept isimo hormone yesimila ngokuthi "omuhle" noma "omubi", eziningi inkulumo udokotela abanekhono ezaziwayo. Kodwa lapha bebodwa, lezi zincazelo musa ezihlobene imizwelo, indoda elula emgwaqweni kungaba kanjani ukucabanga, eqala ukuzwa mayelana CGS-cwaningo. Ukwambula isimo esihle gertsept kubonisa ukuthi lolu hlobo lomdlavuza lunamandla kakhulu nemvelo, it is ithuthuka ngokushesha, lisabalalele emzimbeni by Ukudlulela. Kodwa ngesikhathi esifanayo, isimila enjalo ebulalayo nge awokuthi uyosabela ezithile izidakamizwa. izimila Negative isimo gertsept uzokutshela ukuthi unesimila eba kancane, kodwa indlela yokwelashwa ezanele wakhe abuzange.

Immunohistochemistry - kuyini?

Omunye lomdlavuza oluvamile kakhulu phakathi kwabesifazane - umdlavuza webele. IHC cwaningo kusiza ukucacisa uhlobo neoplasm acoshe ukwelashwa ngokuhambisana isimo. Immunohistochemistry - a cwaningo laboratory biopsy (biomaterial, ezithathwe ngesikhathi biopsy) usebenzisa Umbala umphenyi okhethekile. -рецепторы, и чем больше рецепторов, влияющих на появление и развитие "ненормальной" клетки, тем ярче будет окраска исследуемого биоматериала. Le into amabala YENA R-2 ama-receptor, futhi ama-receptor ngaphezulu ezithinta ukubukeka nokuthuthukiswa kwamaseli "normal", le licace umbala test biomaterial.

Kangakanani isimo izimila?

biomaterial Painted ngesikhathi ukuhlolwa laboratory ukunquma isimo gertsept kuthiwa zibukeke zihlolwe. Okunanyathiselwe kule esikalini esikhethekile, okuyinto has umbala umyela kusuka 0 kuya 3+. Le ndlela yenza kube lula ukuhlukanisa embundwini ezine eziyinhloko, okuya ngokuthi yikuphi okulindeleke ukuba isiguli ukuhola phambili. Kubonakala - kulula? Ibala nezicubu nge isakhi esithile esikhethekile, ibekwe ngaphansi ngesibonakhulu, cabangisisa Ngokuqhathanisa lokho akubona ukulawula amasampula umbala, bese usetha isimo gertsept yesimila. Kodwa lapha indima enkulu eyadlalwa isici womuntu, ikakhulukazi ukukhanyisa nokunye.

Kangakanani isifundo IHC

Ukuze umdlavuza esolwa isifuba kwenziwe esifundweni. Sokuqonda cwaningo immunohistochemical iqukethe wonke imibundu ezine. Kodwa inkinga ukuthi value isilinganiso ezimbili, futhi kuyoba 1+ futhi 2+ ngezinga elingelikhulu usikisele imphumela engacacile ezidinga kuphenyisiswe ngenye indlela. Lokho cwaningo IGH- - indlela impikiswano kakhulu ukuthola izimila isimo gertsept. Ngaphezu imiphumela yethonya ucwaningo iyasebenza, njengoba sekuphawuliwe, isici abantu futhi yizimo zangaphandle. Into kuphela ukuthi kunqunywe kakhulu ngokunembe ekupheleni yi ezimbili - ezingezinhle 0 (isimila has a isimo gertsept negative) kanye 3+ (omuhle isimo hormone yesimila).

hormone besimame isimila

Njengoba imithi yesimanje, iningi izimila zesifazane uhlelo zokuzala axhomeke amazinga omzimba hormone. ukuthuthukiswa yabo ngentshiseko kuthinte hormone zesifazane - progesterone futhi estrogen. Receptor ngoba la ma-hormone ukucacisa ukubunjwa nokuthuthukiswa kwezinhlangano zomdlavuza. Kufakiwe i-hormone kwencika ukunquma ngokucaca eyanele eziyalezweni ukwelashwa kulandele onalesi sifo kubalulekile. Ngaphezu kwalokho, lezi ezenza ukudlala indima, hhayi nje kuphela Oncology webele, kodwa futhi anjalo ezinkingeni ezingathi sína njengoba ukungazali zesifazane, i-endometriosis futhi umdlavuza yezifo sphere ngokocansi - kwesibeletho, amaqanda, wesibeletho. Gertsept ubulungu isimila, okuyinto lihlelwe phakathi nesifundo IGH- endometrium, isibonelo, linqume ukwelashwa ivumela ngokunembile leyo mithi ezingasiza ukufeza umphumela ezanele ngaphandle nokucwaninga okungadingekile ukukhethwa izidakamizwa ngamunye endabeni ethile.

Uma ukungazali

Okungavundile - iyinkinga enkulu emikhayeni eminingi yesimanje. Ukuqhuba yesayensi nezikhungo zezokwelapha ucwaningo luye lwabonisa ukuthi inombolo ngokwanele enkulu izimo, ukungazali kungenxa yokuntuleka endometrium hormone - ungqimba EPITHELIAL abami ngalo ingaphakathi lesizalo. It isimo gertsept futhi kwembula cwaningo IGH- ka ukwamukela we endometrium. hormone Female ubulili - amasayithi asebenzayo kwetinhlavu neqanda kokukhulelwa yayo, i-embryo selitshalwa kwesibeletho, kanye Ukuthwala alandelayo ekhulelwa noma ebeletha. CGS-Ukutadisha endometrium, njengoba sishilo, lembula isimo gertsept lamaseli endometrial ukuba estrogen futhi progesterone, futhi ngokuhambisana imiphumela ngowesifazane ukuba akhethe imithi ekufanele.

Imiphumela yaloku kuhlola okungenhla lymphoma

Cancer - the abantu enkingeni. Nakuba yesimanje kwemithi lobuchwepheshe ngentuthuko enze kube nokwenzeka ukuba alulame kusuka lezi zifo. Kodwa kuba ukuhlola kubaluleke kakhulu, ikakhulukazi kusaqalwa isifo. lymph Oncology - inkathazo evame kakhulu. IHC cwaningo lymphoma - yezindlela i ukusazi ngokunembile isifo esikuphethe ke lokuqoka yokwelapha ezanele. Lokhu kuhlolwa kwenziwa ku biopsy ka-lymph uketshezi noma izicubu uhlelo hematopoietic. Ayiswe efundwayo is sesimeni ekhethekile Umbala izinto ezisiza ukunquma izimpawu lwesimila. Ngeshwa, le uhlobo locwaningo aluphelele futhi ezimweni eziningi eyayihambisana ezinye izindlela zokuxilonga. Ngaphezu kwalokho, ngokuvamile hhayi uhlelo lymph kubangela izinkinga. Yilokhu wembula IHC Ukutadisha-lymph.

IHC ukuhlaziywa - ngolwazi ngesikhathi esifanele

Izinkinga zempilo kufanele ngesikhathi esifanele sitholakale siyachazwa. Kuze kube yimanje, isidingo nezindlela ezihlukahlukene ucwaningo, ukuhlaziywa. исследование - один из наиболее распространенных методов диагностики новообразований или других проблем с тканями различных органов. cwaningo IGH- - eyodwa yezindlela ezivame kakhulu zokuba uchwepheshe wokuhlola izimila noma ezinye izinkinga nge izicubu izitho ezihlukahlukene. Ucwaningo olwenziwa e-IHC kuthathwe ukunquma izinto ezibalulekile - okubizwa ngokuthi biopsy. Indaba edwetshwe izinto esikhethekile injongo ngayinye ethize futhi ezibukwayo ukuqhathanisa olwenziwa histologists udokotela esungulwe isimila omaka, okubonisa inkinga ethile. Ukungapheleli cwaningo immunohistochemical ukuthi impahla kungase kunganeli ukudlala indima ezibangelwe umuntu noma iziphi izici zangaphandle ngeke sivumele ukusungula swe kahle le nkinga. исследование. Kunoma ikuphi ezanele ukuxilongwa kwesifo, ikakhulukazi Cancer kudingekile ukuba aqhube eziyinkimbinkimbi inhlolovo, lapho omunye izinyathelo IGH- cwaningo. какого-ибо органа, ткани? Kuyini nomdlavuza kwabanye izicubu emzimbeni? Biopsy uphenywa ngoba isimila nakomaka ukuhlola yobukhona babo isampula. Njengoba into elisizo sitholakele IHC cwaningo lubaluleke, njengoba uhlanganyela ngentshiseko esetshenziswa ekusunguleni izimbangela ukungazali zesifazane.

Medicine, futhi zokuxilonga kuhlanganise njalo elokhu ivela. Mhlawumbe esikhathini esiseduze cwaningo immunohistochemical esizayo ngeke siyolethwa ekupheleleni futhi kuzovumela abantu abaningi ukubeka sokutholakala ukuthi une-ezanele kanye nezindleko okungenani isikhathi kanye nemizamo.