"Coronal": izinkomba ukusetshenziswa, ukubuyekezwa. izidakamizwa analogue

Kutfutfukiswa izifo zenhliziyo ihamba kancane futhi waphawuleka kusaqalwa. Mayelana nezinkinga inhliziyo umuntu ezimweni eziningi bazi lapho zokugula iye yathuthuka, futhi umphumela waba ukuthi kwakudingeka esibhedlela esiphuthumayo. izifo zenhliziyo kuyingozi ngoba kwenzeka cishe kungekho zimpawu zokugula. Le miyalezo ingenye yezinto eziyinhloko yokufa emhlabeni. Ngisho noma isiguli ukusinda ekuhlaselweni yokuba nesifo senhliziyo, ukubuyela ngendlela evamile yokuphila akunakwenzeka, ngakho kudingeke zivumelane entsha, isitayela encipha. Vimbela ukuthuthukiswa sengozini yokuthola izifo yesifo senhliziyo kungenziwa, ngesikhathi base sitholakale. Ngakho-ke, kufanele ibhekane beyohlolwa zokuvimbela ukuze balondoloze impilo inhliziyo yakho.

isifo senhliziyo

Kukhona izimpawu eziningana lokho kungase kubonise ukuthuthukiswa nezinkinga zenhliziyo. Ukubona lezi izimpawu kufanele usheshe uye emtholampilo, lapho ukuhlolwa olunzulu kuzosiza ukuxilonga izifo futhi ukuvimbela yezinkinga kungenzeka.

Izimpawu ezivame kakhulu ze-izigaba sokuqala yesifo senhliziyo zihlanganisa ukukhathala, kanye ubuthakathaka jikelele. Zingase ezihlobene nokucindezeleka noma ukucindezeleka okusezingeni eliphezulu, kodwa kungase futhi kube uphawu lokungabi yokumelwa yinhliziyo. Njengomthetho, ukukhathala ngeke iphele ngisho nangemva lonke, futhi wanezela nesinye futhi umuzwa ukudangala, ukungakuthandi ukudla, impilo ebuthaka jikelele. Olunye uphawu ezingase eyobonisa ukuthuthukiswa wamaphaphu noma isifo senhliziyo kuyinto iphika, futhi lesi simo singenzeka ngisho nalapho umuntu usesimweni enokuthula ngokuphelele.

ukwesaba okukhulu, ukucindezeleka noma umsebenzi ngokomzimba isikhathi eside wonke umuntu enempilo kungabangela palpitations inhliziyo, futhi lokhu kubhekwa evamile. Uma tachycardia ngokuvamile ukhathazekile futhi ngaphandle kwesizathu esizwakalayo, singakhuluma khona ukuphazamiseka isimo uhlelo senhliziyo nemithambo yegazi. Ezinye izimpawu yesifo senhliziyo zihlanganisa ukulahlekelwa ibhalansi noma isiyezi okungazelelwe, yokufikelwa, ukungakhululeki kanye ubuhlungu besifuba. Lezi zimpawu yilezi imbangela umuntu ukuya kudokotela. Futhi kudlule luhlolo olunzulu uhlelo senhliziyo nemithambo yegazi.

Izidakamizwa "coronal"

Uma isiguli uye kwatholakala at the stage of isifo senhliziyo, okuyinto akudingi kokuhlinzwa, esasibekelwe imithi. Izidakamizwa yokulwa nesifo senhliziyo kusiza iziguli yokubhekana nezinselele ngezimpawu zesifo bese wehlisa inchubekelembili yayo. Umuntu kudingeka alungele yokuthi uma efuna ukwenza ukuphila kwakhe, kwakumelwe ashintshe nomfanekiso waso, ngokukhethekile, give up imikhuba emibi, ukudla, ukuhlanganisa umthwalo ngokulinganisela nalo lonke.

Namuhla emashalofini Pharmacy eziningi zezidakamizwa okukhomba ekulweni nezinkinga zenhliziyo. Omunye izidakamizwa ezivamile kuyabekwa kukhona "coronal" tablet. Izinkomba ukusetshenziswa zomuthi kungenzeka lokhu okulandelayo: ischemic isifo senhliziyo, arrhythmia, umfutho wegazi ophakeme, ventricular noma supraventricular arrhythmias nabanye. Ngaphambi kokuqala imithi oyinikiwe, kufanele uxhumane nodokotela wakho. Medicine "coronal" kunemiphumela eqinile ngokwanele emzimbeni, has a uhlu contraindications kungadala imiphumela emibi. Itholakala amaphilisi ifilimu-camera. Udokotela angase akunikeze imithi lesi sidakamizwa "coronal" futhi analogue yayo.

kwemithi

I nomuthi "coronal" has antianginal, antihypertensive futhi isenzo antiarrhythmic. Lokhu abakhethayo beta-blocker kunciphisa kumiswa AMP eyindilinga kusukela ATP futhi uyakwazi ivimbela receptor beta-adrenergic zenhliziyo. Futhi, lesi sidakamizwa "coronal" kunciphisa contractility esivimba amanzi nokushaya kwenhliziyo, conductivity yayo futhi excitability.

Umthelela hypotensive zomuthi kubonakala eqinisweni lokuthi kunomthelela ukwehla okukhipha inhliziyo. "Coronal" - ngamaphilisi ukubuyisela ukuzwela ejwayelekile baroreceptors, zivimbela umsebenzi reninangiotenzivnoy uhlelo, kuthinte isimiso sezinzwa esiyinhloko. In iziguli abaphethwe umfutho wegazi ophakeme, inciphise umfutho wegazi ophakeme laligujwa ngemva kwezinsuku ezingu-2-5 ngemuva kokuqala isicelo. Ngemva kwezinyanga 1-2 imakwe hypotensive esitebeleni nomphumela oqabulayo.

Ukulungiselela "coronal", izinkomba lapho babe spectrum ebanzi ngokwanele likwazi ukusebenza antianginal. Tablets ukukhuthaza ukunwebeka diastole ngcono perfusion we imisipha yenhliziyo, ukunciphisa i-oksijini yayo funa ngokunciphisa inani ukushaya kwenhliziyo. Umthelela antiarrhythmic zomuthi yikhono layo ukuqeda izici arrhythmogenic. Ngosizo lwawo siyehla conduction atrioventricular kunciphe izinga excitation we itheku futhi elawula ukushaya kwenhliziyo ethunjini.

Usebenzisa amathuluzi medium-Isikali lingaphansi okukhulu imithambo neuropathy, imisipha abushelelezi bronchi, amanyikwe, imisipha lwamathambo, umzimba carbohydrate. Umuthi akusho alibale ion sodium emzimbeni, ukumuncwa yayo imayelana 80-90%.

izinkomba

Ngaphambi ozithathayo "coronal", udinga ukubonana nodokotela asikisele ubani oyakuninika iziqondiso ezicacile mayelana umthamo kanye nokuvama abaphathi. Awukwazi ukuqala ukuthatha izidakamizwa bebodwa, kukhona ingozi umonakalo empilweni yabo, futhi kwaba nemiphumela engelapheki.

Ngo izidakamizwa izinkomba "coronal" ukusetshenziswa ikakhulukazi kungagcini senhliziyo nomfutho wegazi ophezulu kanye. I umthamo wansuku - 5 mg. The main isithako imithi esebenzayo "coronal" - bisoprolol. Izinga sangemihla se-kuya ku-20 mg, kuyilapho iziguli isibindi kahle umsebenzi evamile - 10 angu. Ulapha kuzo zonke izimo kushintshwe ngamunye, ikhumbula zokwelapha ngempumelelo nokushaya kwenhliziyo. Yehlisa umthamo zomuthi "coronal" kufanele kube kancane kancane, akunakwenzeka ukuyeka ukuthola Yiqiniso ngokuzumayo. Lokhu kuyiqiniso ikakhulukazi iziguli pectoris angina (CHD).

Izimo

Kukhona uhlu izimo lapho kungcono ukulahla ukusetshenziswa "coronal" izidakamizwa. Izinkomba Zokusetshenziswa yesifo senhliziyo kungase kungabi isici kuphela, ukuze ukuqala indlela yokwelashwa. Udokotela kufanele ngokucophelela futhi kahle ukuhlola isiguli ukuphepha lakamuva.

Umuthi is contraindicated in iziguli decompensated inhliziyo ukwehluleka, ukwehluleka oyingozi inhliziyo, ukushaqeka cardiogenic, cardiomegaly, angina Prinzmetal, SSA syndrome, vimba atrioventricular II-III ekhulwini., Ukuvinjelwa Sinoatrial. Ningaphathi esebenzisa "coronal" ezigulini babe ukuzwela umuntu emuthini. It is hhayi Kunconywa ukuba linqume ukuba abesifazane ngesikhathi lactation, kanye kuhlanganiswe nokusetshenziswa mao inhibitor.

Ezimweni ezimbi kakhulu, kodwa kulokhu ukulungiselelwa ngokucophelela kakhulu esetshenziselwa ukwelapha iziguli nge myasthenia gravis, claudication ngakanye, syndrome ka Raynaud, ukwehluleka hepatic, ezingamahlalakhona ukumelwa inhliziyo, pheochromocytoma, lactic umzimba, isifuba somoya bronchial, emphysema, isifo sikashukela. Izimo ukusetshenziswa kungaba ukucindezeleka, psoriasis, i-hyperthyroidism, ebuntwaneni nokuguga, ukukhulelwa. Qondanisa indlela "coronal" izidakamizwa (impendulo evela kodokotela kuleli bukhomba) ngesikhathi sokukhulelwa kungabangela ukukhubazeka kuphela kube njalo lapho inzuzo umama izikhathi eziningana ephakeme ukwedlula kwabo engozini ngoba nje ingane.

ukweqisa izidakamizwa

Isiguli kumele ngokuqinile nezidingo onguchwepheshe, ngoba ukweqisa izidakamizwa kungabangela izimpawu eziyingozi. izimpawu engeziwe ezivamile ezibangwa ukweqisa izidakamizwa kusho "coronal" - bronchospasm, ukuhluleka kwenhliziyo, hypotension, bradycardia. Ukudakwa kubangela ezinzima cardiodepressivny umphumela ukuthi ubusa ngaphezu ukwehla contractility nokuncipha kwenhliziyo. Isiguli angagcina disorder zokuphefumula ezazibangwe bronchospasm.

Uma isiguli ukuphendula ezingezona ezemvelo ukuba umuthi, kufanele ngokushesha ukuthatha izinyathelo iwukudambisa kubo. Into yokuqala okumele uyenze - ke ukwenza lavage esiswini kulandele ekuphathweni ehnterosorbentov (namalahle ocushiwe). Futhi ukuphuza laxatives (i-sodium sulfate). Ongaqeda izimpawu zokudakwa usebenzisa atropine (0.5 -2.0 mg) ngemithambo yegazi. Futhi kulezi zimo ukusebenzisa glucagon 1-5 mg. Ngezinye okuvela bronchospasm udinga ukusebenzisa bronchodilator izidakamizwa (aerosol "salbutamol" noma "Fenoterol").

side effects

Ukulungiselela "coronal" kungabangela imiphumela eminingi engemihle njengezindlela ayisukumele wonke umzimba. Engozini yilena:

• Isimiso senhliziyo nemithambo yegazi;
• isimiso sezinzwa;
• umgudu wokuphefumula;
• pheshana emathunjini;
• uhlelo urogenital;
• ama-apharathasi ezibukwayo;
• isikhumba, imisipha, amalunga omzimba.

On the ingxenye esimiso senhliziyo nemithambo yegazi yezinkinga ezifana kungenzeka ngezinye izikhathi, njengoba paresthesia, conduction neziyaluyalu, bradycardia, umfutho ophakeme wegazi orthostatic uphinde wehlise blood pressure. In iziguli phenomenon Raynaud noma claudication ngakanye siba sibi izimpawu.

Umuthi "coronal" side effects kanye kungabangela isimiso sezinzwa, okungukuthi, izinguquko ngokwengqondo, amaphupho acacile, unenkinga, isiyezi, ubuhlungu bekhanda, ukukhathala. Kakhulu akuvamile, kodwa namanje ku-apharathasi ezibukwayo kungayithonya indlela "coronal". Uphenyo kulawa, enqwabelene, kodwa ngenxa ukuchayeka izidakamizwa zingase zibe zimbi umbono, Ukubhidliza encishisiwe, kuze ukuthuthukiswa conjunctivitis.

Izimpawu ezifana bronchospasm, dyspnea, rhinitis, futhi acinene ukuminyana ungase uphazamise kulezo ziguli abaphethwe somoya bronchial. Ezimweni ezingavamile kwenzeka imiphumela hepatotoxic ka bisoprolol, okuyinto kunqunywa isicanucanu, uhudo, ukuqunjelwa kanye ubuhlungu besisu.

Phakathi kwezinye imiphumela emibi kubangelwa isenzo izidakamizwa "coronal" Izibuyekezo nesineke uqaphele lokhu okulandelayo: anda ukujuluka, ukulunywa futhi ububomvu kwesikhumba, arthropathy, amajaqamba kanye muscle ubuhlungu. Akuvamile ekukhathaza dysuria futhi Erectile Dysfunction kubangelwa isenzo "coronal" izidakamizwa. Analogs futhi izidakamizwa kungabangela imiphumela eminingi engemihle njengezindlela emzimbeni. Ngakho-ke, esimweni ngasinye, qiniseka bonana nodokotela wakho kuqala bese ulandela imiyalo yakhe.

Izixwayiso

Ngaphezu contraindications side effects, kukhona eziningi ezimweni lapho ukusetshenziswa kwezidakamizwa uqaphe kakhulu futhi njalo ngaphansi kokuqondisa kukadokotela. Kuyinto akhathalela ngokuyinhloko izimo ezifana congestive inhliziyo ukwehluleka, isifo sikashukela, ukucindezeleka, myasthenia gravis, psoriasis, i-hyperthyroidism, ukuphazamisa ukusebenza evamile, isibindi, noma izinso, lactic umzimba, indlala, Prinzmetal angina.

Okungalapheki izifo obstructive zokuphefumula kusho "coronal" analogue nezinye beta-blocker zingafundwa, kodwa kuphela lihambisana bronchodilators kanye ngemithamo omncane. izindlela Feohromotsitome kumele kuthathwe kanye kanye nokuvinjelwa la mangqamuzana-alpha-adrenergic. Umthamo kufanele sinikezwe sekuhloliwe kwesibindi nezinso.

Kwegazi izidakamizwa kungenziwa kuphela iphathwa ngaphansi kweso lwezokwelapha njalo. Kwehliswe adrenergic ukusabela kontrregulyatsii futhi anaphylactic babhebhethekise Yiqiniso ukusabela ezigulini ukuthatha beta-blocker. ezigulini esezikhulile futhi kungenzeka sensitivity high ngisho nalapho esebenzisa Ukweqiwa evamile zomuthi, ngakho-ke udinga ukuqapha njalo.

Uma ufuna ukuhlinzwa kobuholi, ukusetshenziswa kwezidakamizwa khansela amahora angu-48 ngaphambi kokuba uhlinzwe, ngesikhathi esifanayo musa ukwenza kanjalo ngokushesha, kodwa kancane kancane. Uma isiguli sine-izidakamizwa izinkomba "coronal" ukusetshenziswa, ke kudingeka aqikelele kakhulu emisebenzini edinga izinga okusezingeni eliphezulu ukusabela ngokomzimba nangokwengqondo (yokusebenza ezindaweni eziphakeme, besebenza ngemishini, umsebenzi kanye nemishini eyingozi, ukushayela, njll).

izidakamizwa ekuhlanganyeleni

Ukuthatha "coronal" (amaphilisi) ngesikhathi esifanayo nezinye izidakamizwa kufanele ihambisane siphephe. Ikakhulukazi kumayelana inhlanganisela nge Mao inhibitor iye yabonakala emva ekunqanyulweni kwe blood pressure. Ukuhlanganisa beta blocker nge allergen ezikhishwe ukuhlolwa isikhumba nge nomzimba esetshenziselwa immunotherapy, kukhona ingozi ingqondo ukusabela kabi komzimba nomzimba.

Ngo ukusetshenziswa antiarrhythmics amakilasi mina no-III ( "Dizopiramid", "Sotalol", "Quinidine" "Amiodarone", "Lidocaine") futhi kudingeka uqaphe. Lapho ukuphatha kanyekanye izidakamizwa antihypertensive kanye amaphilisi "coronal" the sakamuva singabangela potentiate imiphumela wokuqala. Uma ukusetshenziswa kwalesi izidakamizwa lihambisana "Guafatsinom", "digitalis", "Clonidine", "reserpine", kungaba ukubambezela ngokubamba uhlelo conductive wenhliziyo pulses kagesi.

kusebenta zokwelapha ukulungiselela "coronal" kungenzeka kahle nge ukuchayeka ejenti sympathomimetic (izidakamizwa antitussive, acinene noma ngeso amaconsi). Activators enzyme hepatic liyochukuluza wokwehla begazi isigamu-nokuphila we-beta-adrenoceptor agonist. ekuphathweni esisodwa izidakamizwa antiarrhythmic, futhi -calcium channel blocker amaqembu "Nifedipine" futhi "Verapamil" kungabangela bradycardia, ukuhluleka kwenhliziyo noma conduction thuthuva.

ukwelashwa kanye kanye nezidakamizwa "coronal" futhi "Clonidine" kungabangela ukuthuthukiswa esibucayi abanomfutho wegazi ophakeme. Uma yokwamukela izidakamizwa ukufundwa "coronal" ube iziguli sikashukela, it is kakhulu Kunconywa ukuqapha njalo amazinga igazi glucose. Lokhu kungenxa yokuthi i-beta blocker kungaba potentiate umphumela kwemishanguzo elwa sikashukela kanye insulin, ukugqiba izimpawu kahle kungakhuphula izinga likashukela.

Uphenyo imithi

Izidakamizwa "coronal" odokotela linqume ukuba iziguli isifo senhliziyo. Kodwa uma kunjalo konke lokhu imithi isebenze? Ukuhlaziya ukubuyekezwa ngakho, ungenza isiphetho jikelele ukuthi umthelela isidakamizwa umzimba lesiguli incike ngamunye icala ngabanye. Labo nenhlanhla ngokwanele yini ukubhekana nemiphumela emibi omuhle kakhulu ukulungiswa "coronal". Izibuyekezo iziguli abaye bazizwa imiphumela zomuthi, akuyona kamnandi kangaka. Nokho, izinkinga kungagwenywa. Ngaphambi ozithathayo "coronal" (amaphilisi), isiqondiso kumele ngokucophelela kabusha funda izikhathi eziningana, ngoba budedengu Ungakwazi futhi zilimaze impilo yakho.

Into yokuqala ukuthi iziguli uthi lokhu ukwehla kwenhliziyo, ukuncipha kancane wegazi, ngcono isimo jikelele isiguli. Ngemva kwezinyanga eziningana isicelo, odokotela batusa ukuba kuncishiswe umthamo, ngoba ukushaya kwenhliziyo nomfutho wegazi ifinyelele kuyinsakavukela futhi asikho isidingo ukwehlisa owengeziwe kubo. Iziguli futhi uqaphele ukuthi uma ulandela zonke iziqondiso udokotela, nemiphumela ebuhlungu kufanele ungesabi zomuthi. Kodwa labo ngokuzimela banquma ukuzihlela kabusha izinto umthamo wansuku zonke noma kuhlulekile ukuxwayisa odokotela mayelana nokusetshenziswa nezinye izidakamizwa, sibhekene yezinkinga, nakho ezimweni eziningi kudingeka ukuba aye esibhedlela. Yingakho akufanele sikhohlwe ukuthi kukhona e iphakethe amaphilisi "coronal" imfundo manual ngamunye.

Ama-analogues

Isidakamizwa esithi "Coronal" sinemibono ehlukahlukene yezidakamizwa - izidakamizwa, lapho kunezinto ezifanayo ezisebenzayo. Zonke zihlukile ngamanani, ezweni lokukhiqiza, indlela yokuchayeka, ukuphikisana, ukutholakala noma ukungabikho kwemiphumela emibi.

Njenganoma imuphi umuthi, i-Coronal nayo inomkhakha wayo wokusebenza. Ama-analogs ayo afana nalokho okusebenzayo - i-bisoprolol. Okuvame kakhulu ukulungiselela ukukhiqizwa kwekhaya. Inzuzo yabo iyinani eliphansi (kuqhathaniswa nokungeniswa) nokusebenza kahle. Ngokuyinhloko, ungabhala izidakamizwa ezinjalo: "Aritel", "Aritel Kor", "Biprol", "Bisoprolol", "Bisoprolol-Prana", "Niperten". Zitholakala kuwo wonke ama-pharmacy kiosk, kanye namanani abo amanani kusukela ku-30 kuya ku-100 ruble iphakheji ngayinye.

Ukungenisa izifaniso zokulungiswa kweCoronal nazo zenziwa ngezindlela ezihlukahlukene: iBivop (Hungary), iBool (Slovenia), iBisogamma (eJalimane), i-Bisocard (Poland), i-Bizomor (India), iBisoprolol- Lugal "(Ukraine)," iBisoprolol-Teva "(Israyeli) nabanye. Okuthandwa kakhulu phakathi kwezidakamizwa ezingenisiwe yiMithi yaseJalimane i-Concor. Inani lalo liphindwe kasikhombisa ngaphezu kwezindleko zezidakamizwa zeCoronal futhi liyi-ruble engama-180. Ngokuvamile, izidakamizwa ezingenisiwe kuma-pharmacy kiosks zinikezwa ngamanani avela kuma-ruble angu-300 kuya kwangu-600 iphakheji ngalinye.