"Artrozan": yokusetshenziswa

"Artrozan" yokusetshenziswa libhekisela esigabeni emitholampilo kwemithi ye oxicams. The main izidakamizwa esebenzayo ekulungisweni - meloxicam okungukuthi abakhethayo Cox-2 inhibitor ngempumelelo. Onesihloko esithi "Meloxicam" lokhu izidakamizwa ibhalisiwe encwadini okubhalwa kuyo INN.

Ifomu i-tablet ye-izidakamizwa senziwa ku amaphilisi enesisindo 15 mg noma 7.5 awafaka amabhamuza metering nentaba.

Ngu izakhiwo kwemithi imithi "meloxicam", kokuba ethathwe enolievoy izidakamizwa acid, indlela isenzo eqeda ukuvuvukala kanye analgesic. Le ndlela yokwenza kusekelwe ikhono zomuthi ekuvimbeleni inqubo Kuhlanganisa prostaglandins. Ngaphansi kwethonya ukusabela izidakamizwa kwenzeka, phakathi kwesikhathi lapho ngokukhetha zivimbela umsebenzi Cox-2 ama-enzyme, okuyinto iqhaza biosynthesis main.

Nakuba ngokuthatha izidakamizwa, "Artrozan" Umhlahlandlela uchaza isenzo yalo ngale ndlela. Uma imithi iqondiswa ebulilini, bese phakathi kwenkathi ende ukusebenzisa kwabo ukwehla ngo selectivity ngoba Cox-2. Umuthi kancane kuthinta Cox-1, esivikela pheshana emathunjini. Yilokho ngenxa lesi senzo sokukhohlwa evikelwe pheshana emathunjini kusukela erosive kanye izilonda emathunjini.

I anti-inflammatory izidakamizwa umphumela "Artrozan" imfundo manual ixhuma nokucindezela enzyme umsebenzi Cox-2, okuyinto ethatha ngokuhamba ukuvuvukala.

Pharmacokinetics "Meloxicam" libhekene kanje. Ukusabalalisa "Artrozan" wakwazi ukunqoba izithiyo umzimba-izicubu, ngenxa yalokhu kwakwakhe ne-plasma amaprotheni eliphezulu njengoba 99%. Ukwakheka lwamalunga uketshezi lokuhlushwa ukubaluleka kulokhu 50%.

Umzimba: Umuthi akheka cishe ngokuphelele kumaseli isibindi, ngaleyo ndlela kukhona kumiswa nemikhiqizo eminingana pharmacologically hlangothi.

Excretion: Umkhiqizo "meloxicam" kubonisa mayelana namasheya alinganayo ikakhulukazi umchamo kanye endleni ngesimo imikhiqizo umzimba. 5% kuphela izingxenye kuyinto okukhiphayo kusukela amathumbu.

I izakhiwo pharmacokinetic zomuthi "Artrozan" imfundo manual futhi inquma ngoba ezimweni ezikhethekile. Ikakhulukazi, iziguli esezikhulile lapho ithola imvume encishisiwe zomuthi, futhi esimweni izimpawu ukwehluleka hepatic futhi kwezinso, umuthi umphumela ongeyona inyama phezu pharmacokinetics.

Ukulungiselela "meloxicam" is kahle ugxile kusukela ipheshana emathunjini, uhlelo bioavailability level yayo ifinyelela 89% futhi ayithinteki ukudla. Reception ngemithamo umthamo ekhiqizwa inikeza lokuhlushwa ezilinganiselwe zomuthi emzimbeni.

Distribution: Ngokuvamile, ukusebenza elilungile CSS senziwe eyesithathu Ngosuku lwesihlanu kwezokwelapha, ngesikhathi ukusetshenziswa yayo yesikhathi eside kunikezwa lokuhlala esitebeleni ufana kokuqala pharmacokinetic nemingcele.

Umthamo lesi sidakamizwa "imiyalelo Artrozan 'ukusetshenziswa kunqunywa kanje.

Sebenzisa izidakamizwa ngefomu kuhlanganiswe Kunconywa. Isimiso Kunconywa:

- in the esigabeni sokuqala ukwelashwa, izinsuku 2-3, isicelo "Artrozan" -ukoly;

- emva kwezinsuku ezintathu noma ezine esicutshini abaphathi kufanele kusishukumisele ukuze bathole imishanguzo engabasiza ngomlomo - ngesimo amaphilisi.

Umthamo kwezokuphatha esicutshini, futhi abaphathi temlomo kuyafana futhi ilingana okujwayelekile (7.5 noma 15 mg) kanye nsuku zonke izinsuku. Umthamo kanye nesikhathi isicelo enqunywe ukushuba ubuhlungu kanye nezinga kobukhulu ukuvuvukala. Ekunqumeni umthamo okufanele zithathwe ngokucophelela ku-akhawunti ingozi engaba ngenxa yezinkinga ezivela pheshana emathunjini.

Ephambi kwezinduna ukwehluleka kwezinso, umthamo wansuku zonke esiphezulu ezingekho ngaphezu 7.5 mg.

Ukusebenzisana neminye imithi kungenzeka nzima okuvela kuyo imiphumela erosive-ulcerous e pheshana emathunjini. Musa thatha izidakamizwa ngenkathi bekhulelwe nangenkathi bencelisa.

Umkhiqizo "Meloxicam" kumele agcinwe endaweni emnyama iminyaka engaphezu kwemibili.

Izidakamizwa ithengwa kadokotela kuphela.