Analogue eshibhile futhi ngempumelelo "Traneksama"

Abantu abavamile kanye neziguli kanye hematological nezinye izifo igazi ivame ukubhekana ingozi ezinzima noma ezisongela ukuphila ukopha ngenxa ongaphakeme platelet count. Lokhu akufanele kuphela kubangelwa isifo eziyinhloko zegazi, kodwa futhi kusukela umphumela anobuthi e kuyofika emnkantsheni ithambo emva kokwelashwa. iziguli anjalo abelwa ukuhlaziya injongo zokuvimbela yokumpontshelwa igazi nemikhiqizo yegazi ukuvimbela ukopha.

Lezi ukumpontshelwa akuzona ngaphandle yezinkinga zenzeka, ezisukela ukusabela omnene ezifana imfiva kanye lubucayi kakhudlwana, noma ngisho esisongela ukuphila nemiphumela, ezifana ukutheleleka, ngobulili kusukela nesineke elampontshelwa platelet naphezu ubambe amasampula ezahlukene ukuhambelana. Ukuze ekwelapheni ukopha okwamanje kabanzi "Tranexam" noma "Tranexamic acid" noma okulingana "Traneksama" - "aminocaproic acid".

antifibrinolytic Isicelo

Ngokusobala, izindlela ukuvimbela ukopha iziguli, kanye ukunciphisa imithelela platelet elampontshelwa Uyokwamukelwa. Enye indlela kungenzeka ukuthi afeze lezi zinhloso ukusebenzisa antifibrinolytic eyaziwa ngokuthi lysine analogs "Tranexam" futhi "aminocaproic acid". Le mithi esiza ekulinganiseni amahlule ukuthi yakha emva ukopha, okuyinto kunciphisa kakhulu amathuba ukopha eminye kanye nesidingo ukumpontshelwa platelet.

Kodwa kodwa kungase futhi kube izingozi ezihlobene ukusetshenziswa kwalezi izidakamizwa, ebaluleke kunazo zonke okuyinto kwengozi kumiswa engathandeki amahlule kanye nesenzakalo izifo (ezifana deep vein thrombosis) okungase esisongela engase ukuphila. Isicelo antifibrinolytic uhlobo nokulungiselela "Tranexam" analogs okuyinto "aminocaproic acid," "Dicynonum", "Etamsylate", "Vikasol" kunganciphisa ukopha ukuvimbela ukumpompela platelet.

isidingo ukusebenzisa

Iziguli ezinokuphazamiseka hematological nokopha isici ukuthuthukiswa thrombocytopenia nemibandela ezinzima noma ezisongela ukuphila. Lena naphezu kokumpontshelwa igazi ukuvimbela ukopha lapho platelet count lize liba ngaphansi kwe kombundu ethile. Kodwa kungaba esisongela ukuphila ngenxa yezinkinga eziningi. A kwalokho kungenzeka ukusetshenziswa prophylactic ukumpontshelwa kuyinto antifibrinolytic, okungukuthi lysine analogue "Traneksama" futhi "aminocaproic acid."

"Tranexam". Yokusetshenziswa

Analogue lokhu acid kukhona ifomu eyenziwe i-asidi amaprotheni amino ngokuthi lysine. Le mithi ukuvimbela ukubhujiswa amahlule emzimbeni by ekuvimbeni enzyme. Nakuba lesi sidakamizwa "Tranexam" analogue nama esikhundleni ukusetshenziswa kwalo ekwelapheni esindayo ukopha kokuya esikhathini, kodwa musa ukususa premenstrual syndrome, futhi asetshenziselwa ukuvimbela ukopha abantu hemophilia, okuyilona elidingekayo ukuze ususe izinyo. Lo muthi ngokuvamile inikezwa hhayi kuphela inqubo wamazinyo, kodwa futhi malanga onkhe kufikela kuzinsuku ezingu-8 ngemva kwalokho. Ngaphambi kokusebenzisa lo imithi kufanele azise udokotela mayelana nokuba khona isifo sezinso, wegazi, i-endometriosis noma uma imijikelezo kokuya esikhathini sezinsuku esingaphansi 21 noma izinsuku isikhathi eside kunaleso 35.

Akufanele ukuqala Ngokuthatha "Tranexam" nozakwabo nyangazonke. Izibuyekezo ekubulaleni iziguli ezigulela self-iqondiswa mithi ngokwabo, bathi ukopha awutholi ezincane. Ungayisebenzisi izinsuku ezingaphezu kuka-5 elandelanayo phakathi nenyanga. Uma izimpawu musa ngcono ngemva ezimbili ngemijikelezo ukwelashwa, zidinga ukuqondiswa yokwelashwa noma ukusihlola. Ungathathi amaphilisi angaphezu kuka-6 ngosuku.

zokuvimbela inzalo kwama-hormone (isib zokuvimbela inzalo amaphilisi, imijovo, implatanty futhi amasongo sowesifazane sangasese) kungase kwandise ingozi yokushaywa unhlangothi, thrombus noma ukuhlaselwa yinhliziyo uma bewasebenzisa ngesikhathi esifanayo njengoba Analogue "Tranexam". Akufanele ukwabelana imithi nomunye umuntu, ngisho noma izimpawu ezifanayo njengawe. Libuye engathandeki ukusebenzisa noma isiphi Analogue "Tranexam" amaphilisi, uma une-yokungezwani komzimba ukuze izingxenye izidakamizwa, futhi propensity kuya thrombosis, isifo sohlangothi kanye yinhliziyo.

kuthiwa Kungani le mithi kuyabekwa

"Tranexamic acid" futhi Analogue "Traneksama" - "aminocaproic acid" inikezwe nigweme ukusaphaza okwenzeka ngesikhathi amahlule nagazi akunakulidla yakha noma ngokushesha wabhubhisa. Lolu hlobo lwe-ukopha kungenzeka:

• phakathi noma ngemva kokungenela kuhlinzwa inhliziyo, isibindi;
• e abantu abanalo izifo ezithile ukopha;
• umdlavuza wendlala yabesilisa, iphaphu, esiswini, futhi wesibeletho;
• kwabesifazane abakhulelwe abaphethwe lamabutho kwanoma placenta ngokuvamile ikhona.

"Tranexam" analogue yayo nazo zisetshenziselwa ukunqanda ukopha e ngomgudu womchamo, okungase kwenzeke ngemuva kokuhlinzwa phezu wendlala noma izinso, noma abantu abanale ezithile zomdlavuza. Le mithi akufanele isetshenziswe ukwelapha ukopha eqonda coagulation intravascular. Kungashiwo okufanayo sathathelwa indawo 'Tranexam "? Analogue of eshibhile futhi kufinyeleleke kalula - ke 'aminocaproic acid, "" Dicynone "," Etamsylate ". It 'aminocaproic acid "ungaphakathi isigaba izidakamizwa ebizwa hemostatics, futhi nomphumela ofanayo njengoba" Tranexam ", ukuthi isebenza ngezindlela ukubambezela Ukugaya thrombus.

Indlela le imithi kumele kusetshenziswe

"Aminocaproic acid" senziwa ngesimo amaphilisi izixazululo (uketshezi) I-ukungenisa. Ngokuvamile kuthatha ekuqaleni 5 g esisodwa, bese uma ihora ukuthi 1 g amahora ayi-8 noma kuze kufike leso sikhathi kuze kube izitobhi ukopha. Lapho "aminocaproic acid" isetshenziswa ukwelapha ukopha eqhubekayo, ngokuvamile ezithathwe njalo emahoreni 3-6. Musa thatha izidakamizwa ucishe noma ukuthatha izikhathi ezingaphezu enqunywe udokotela wakho.

Shake ibhodlela ngaphambi kokusebenzisa ngakunye uhlanganise kahle umuthi. Udokotela angase akunikeze imithi ebulilini aminocaproic acid --24 g ngosuku futhi kancane kancane kuyancipha umthamo kuya ukopha stop.
"Tranexam" analogue "aminocaproic acid" yaso nayo ngezinye izikhathi asetshenziswa ukwelapha ukopha iso, okuyinto kwabangelwa ukuhlukumezeka. Lo muthi ezingahle zinqunywe nezinye izinjongo.

izinyathelo zokuqapha

Ezinye izimo nezifo ukuphathwa izidakamizwa is contraindicated. Lena ezimweni lapho kukhona:

• iguliswa "aminocaproic acid" noma isiphi esinye isidakamizwa;
• isiguli kuthatha Factor IX, Factor IX eziyinkimbinkimbi noma anticoagulant kulokulukhuni
• ukuthambekela thrombosis;
• sokukhulelwa, isiguli uhlela ngikhulelwe noma ukuncelisa ibele.

Kuthiwani uma izidakamizwa sishoda

Kulokhu-ke kuyadingeka ukuthatha umthamo aphuthelwe ngokushesha ngangokunokwenzeka ukukhumbula. Nokho, uma kuba pheze isikhathi umthamo olandelayo, weqa umthamo aphuthelwe bese uqhubeke njalo nokushintsha kokudla nokufakwa schedule. Ungathathi umthamo double ukwenza i-aphuthelwe.

Yiziphi imiphumela emibi

"Aminocaproic acid" futhi kungadala nemiphumela engemihle. Ziyakwazi:

• isicanucanu;
• ukuhlanza;
• ubuhlungu esiswini noma amajaqamba;
• isifo sohudo,
• black, hlalani indle;
• ukopha kwezinsini;
• ikhanda;
• isiyezi;
• ukudideka;
• ukusangana;
• ukuvuvukala izingalo, izandla, izinyawo, amaqakala noma imilenze ephansi;
• Ukuwohloka noma angaboni kahle;
• enkeneneza ezindlebeni.

Eminye yale miphumela engemihle ingase ibe mibi. Uma uhlangabezana nanoma yiziphi lezi zimpawu, kumele ngokushesha ayeke ukuthatha izidakamizwa:

• ukuqubuka;
• ukulunywa;
• ecinene noma ukugwinya;
• ukuba buthakathaka kwezicubu;
• ukukhathala;
• iphika;
• ubuhlungu ngokucindezelwa noma constricting esifubeni;
• ukungakhululeki ku izandla, izingalo, emahlombe, entanyeni noma emuva engenhla;
• ukujuluka ngokweqile;
• umuzwa wobukhulu, ubuhlungu, ukushisa kanye / noma ukuvuvukala emilenzeni noma indishi;
• ukuluma okungazelelwe, coldness ezandleni noma ezinyaweni;
• nobunzima ngenkulumo;
• ukozela okungazelelwe;
• ubuthakathaka okungazelelwe noma ukuba ndikindiki ezandleni noma ezinyaweni;
• iphika;
• ubuhlungu obuhlabayo uma ukudonsa umoya kakhulu;
• ukusheshisa noma okwehlisa we ukushaya kwenhliziyo;
• ukukhwehlela igazi;
• nokugqwala-ezinemibala umchamo;
• kuncishiswe inani umchamo;
• yokufikelwa;
• Ukudlikizela.

uhlangothi okunjalo nemiphumela futhi kungabangela "Tranexam". amaphilisi Okufanayo "aminocaproic acid" kungaba naso singaholela ezinkingeni. Ezinye iziguli zingase zibhekane imiphumela engemihle ngokuvamile awadingi kokungenela wezokwelapha. Zingase zinyamalale imithi oyinikiwe. Udokotela kufanele uxwayise mayelana izindlela zokunqanda noma ukunciphisa ezinye yale miphumela engemihle.

Ukungavumelani nokwelashwa zokuqapha

Umuthi aluhambisani ne-penicillin elwa namagciwane, tetracyclines, ingqamuzana legazi elibomvu, ama-ejenti antihypertensive, "diazepam", "dipyridamole". Ngo isicelo nge haemostatic izidakamizwa thrombotic potentiation umphumela kwenzeka.

Kubalulekile kakhulu ukulawula inqubo igazi ekunqandeni ngesikhatsi ukwelashwa. Lokhu kudinga ukuhlolwa igazi ukubona ukuthi imithi isebenza kahle futhi awekho imiphumela emibi.